Ryan Reynolds as Michael Waechter

Willem Dafoe as Charles Waechter

Emily Watson as Jane Lawrence

Julia Roberts as Lisa Waechter

Hayden Panettiere as Young Jane

Carrie-Anne Moss as Kelly Hanson

Cayden Boyd as Young Michael Taylor

Ioan Gruffudd as Addison

Shannon Lucio as Ryne

Chase Ellison as Christopher Lawrence

Brooklynn Proulx as Leslie

George Newbern as Jimmy

Diane Perella as Flight Attendant

Natalie Karp as Social Worker

Babs George as Nana

Frank Ertl as Morgan Duncan