Flula Borg as Officer Doug (voice)

Alex Cazares as Staci (voice)

Rhys Darby as Happy Sedengry (voice)

Pierce Gagnon as Timothy Templeton (voice)

Jake Green as Bootsy Calico (voice)

JP Karliak as Boss Baby (voice)

Hope Levy as Mom / Peg (voice)

Wendie Malick as Wendi (voice)

Victor Raider-Wexler as Frederic Estes (voice)

Kevin Michael Richardson as Jimbo (voice)

Sarah-Nicole Robles as Marisol (voice)

Brandon Scott as Hendershot (voice)

Eric Bell Jr. as Triplets (voice)

Cynthia Erivo as Turtleneck Superstar (voice)

Jeff Bennett as Puzzle Computers (voice)

Diedrich Bader as Junior Fancy (voice)

James Patrick Stuart as Wagby (voice)

Kari Wahlgren as R&D Baby Simmons (voice)