Chris Pratt as Garfield (voice)

Samuel L. Jackson as Vic (voice)

Hannah Waddingham as Jinx (voice)

Ving Rhames as Otto (voice)

Nicholas Hoult as Jon (voice)

Cecily Strong as Marge Malone (voice)

Harvey Guillén as Odie (voice)

Brett Goldstein as Roland (voice)

Bowen Yang as Nolan (voice)

Snoop Dogg as Maurice (voice)

Janelle James as Olivia (voice)

Angus Cloud as Snickers (voice)

Jeff Foxworthy as Zapped Bird (voice)

Eugenia Caruso as Maria (voice)

Luke Cinque-White as Vito (voice)

Dev Joshi as Liz (voice)

Chana Keefer as Rom-Com Woman (voice)

Mark Keefer as Rom-Com Man (voice)

Edward Montgomery as Fitness Bike Instructor (voice)

Mark Dindal as Sleep App Voice (voice)

Cameron Bernard Jones as Barry / Lactose Farms Phone Operator (voice)

Darren Foreman as Used Catapult Customer (voice)

Timothy Quinlan as Find My Pet Voice (voice)

Matt Rippy as Spanish Find My Pet Voice / Farmhand (voice)

Alicia Grace Turrell as Ethel / Lactose Farms Phone Operator (voice)

Eric Loren as Roadkill / Busboy (voice)

Melli Bond as Fish Market Worker (voice)

Lynsey Murrell as Tour Guide Tracy (voice)

Amelia Sciandra as PA Announcer (voice)

Jennifer Woodward as PA Announcer (voice)

Hannah Felix as Pound Worker (voice)