Ryan Reynolds as Monty

Anna Faris as Serena

Justin Long as Dean

David Koechner as Dan

Luis Guzmán as Raddimus

Chi McBride as Bishop

John Francis Daley as Mitch

Kaitlin Doubleday as Amy

Rob Benedict as Calvin

Alanna Ubach as Naomi

Vanessa Lengies as Natasha

Max Kasch as T-Dog

Andy Milonakis as Nick

Dane Cook as Floyd

Jordan Ladd as Danielle

Emmanuelle Chriqui as Tyla

Wendie Malick as Monty's Mom

Monica Monica as Dean's Mom

Travis Resor as Chett

J.D. Evermore as Redneck

Clay Chamberlin as Video Host

Skyler Stone as Cook #1

Melissa Morgan as Bitchy Lady

Don Brady as Old Man

Anne Ewen as Girl at Bar

Pat Hazell as Jack

Jordan Werner as Smooth Guy #1

Skylar Duhe as Girly #1

Ann Marie Guidry as Dessert Woman

Lauren Swinney as Elderly Woman

Wayne Ferrara as Rocco

Richard Netzberger as German #1

Roland W. Hoffman as German #2

Sandra Marling as Commenting Girl

Dean Shull as Commenting Guy

Melissa Alonzo as Stunt Bush

Todd Voltz as Background Cook

Robb Conner as Background Cook

Matt as Background Cook

Shedric as Background Cook