John Candy as James Harlow

Richard Lewis as Phil Taylor

John C. McGinley as Julian

Ellen Greene as Belle

Robert Picardo as Ben Wheeler

Ed Lauter as John Slade

William Sanderson as Zeke

Rodney A. Grant as Little Feather

Melinda Culea as Constance Taylor

Lochlyn Munro as Billy

Ethan Phillips as Smedly

Charles Rocket as Gen. Larchmont

Don Lake as Lt. Bailey

Joel McKinnon Miller as Zack Ferguson

Russell Means as Chief

Joe Bays as River Townsman

Abraham Benrubi as Abe Ferguson

Ryan Cutrona as Tom

Thomas F. Duffy as Clayton Ferguson

Jill Boyd as Prudence Taylor

Bud Davis as Desperado Leader

Patrick Thomas O'Brien as Stranger

Tony Pierce as Junior Ferguson

Robin McKee as Lindsey Thurlow

Denver Mattson as Card Player

Mauricio Martínez as Card Player

Randy Hall as Pony Express Rider

Douglas Carlson as Bar Patron

Billy Daydoge as Elder

David Dunard as Harry Bob Ferguson

Steve Eastin as Bartender

Roger Eschbacher as Reporter

William Tucker as Reporter

Ingrid Nuernberg as Henrietta Wheeler

Derek Senft as Jeremiah Taylor

Jimmy Ray Pickens as Scout

Chad Hamilton as Ricky Jones

Stuart Proud Eagle Grant as White Cloud

Marcie Smolin as Woman on Trail

Gailard Sartain as J.P. Moreland (uncredited)