Macaulay Culkin as Kevin

Joe Pesci as Harry

Daniel Stern as Marv

John Heard as Peter

Roberts Blossom as Marley

Catherine O'Hara as Kate

Angela Goethals as Linnie

Devin Ratray as Buzz

Gerry Bamman as Uncle Frank

Hillary Wolf as Megan

John Candy as Gus Polinski

Larry Hankin as Officer Balzak

Michael C. Maronna as Jeff

Kristin Minter as Heather

Diana Rein as Sondra

Jedidiah Cohen as Rod

Kieran Culkin as Fuller

Senta Moses as Tracy

Anna Slotky as Brook

Terrie Snell as Aunt Leslie

Jeffrey Wiseman as Mitch Murphy

Virginia Smith as Georgette

Matt Doherty as Steffan

Ralph Foody as Gangster #1 (Johnny)

Michael Guido as Gangster #2 (Snakes)

Ray Toler as Uncle Rob

Billie Bird as Woman in Airport

Bill Erwin as Man in Airport

Gerry Becker as Officer #1

Victor Cole as Officer #2

Porscha Radcliffe as Cousin

Brittany Radcliffe as Cousin

Clarke Devereux as Officer Devereux

D. Danny Warhol as Pizza Boy

Lynn Mansbach as French Woman

Peter Siragusa as Lineman

Alan Wilder as Scranton Ticket Agent

Hope Davis as French Ticket Agent

Dianne B. Shaw as Airline Counter Person

Tracy J. Connor as Check Out Girl

James Ryan as Stock Boy

Ken Hudson Campbell as Santa

Sandra Macat as Santa's Elf

Mark Beltzman as Stosh

Ann Whitney as Drugstore Clerk

Richard J. Firfer as Store Manager

Jim Ortlieb as Herb the Drugstore Clerk

Kate Johnson as Police Operator

Michael Hansen as Airport Driver

Peter Pantaleo as Airport Driver

Jean-Claude Sciore as French Gate Agent

Monica Devereux as Flight Attendant

Edward Bruzan as Polka Band

Frank Cernugel as Polka Band

John Hardy as Polka Band

Eddie Korosa as Polka Band

Robert Okrzesik as Polka Band

Leo Perion as Polka Band

Vince Waidzulis as Polka Band

Quinn Culkin as Girl at Airport (uncredited)

Paula Newsome as Shopper in Supermarket (scenes deleted, uncredited)

Irene Columbus as Woman with Baby on Flight to Paris (uncredited)

Raja Gosnell as Murphy's Answering Machine Voice (uncredited)

Barbie Greiwe as Airline Passenger (uncredited)

Gary Grott as Passenger at desk (uncredited)

Dale Hawes as Airport Traveler (uncredited)

James Huffman as Kid at Airport (uncredited)