Benicio del Toro as Lawrence Talbot

Anthony Hopkins as Sir John Talbot

Emily Blunt as Gwen Conliffe

Hugo Weaving as Inspector Francis Abberline

Geraldine Chaplin as Maleva

Art Malik as Singh

Antony Sher as Dr. Hoenneger

David Schofield as Constable Nye

Cristina Contes as Solana Talbot

David Sterne as Kirk

Elizabeth Croft as Ophelia (uncredited)

Simon Merrells as Ben Talbot

Asa Butterfield as Young Ben

Olga Fedori as Young Gypsy Woman

Lorraine Hilton as Mrs. Kirk

John Owens as Asylum Doctor #1

Gemma Whelan as Gwen's Maid

Nicholas Day as Colonel Montford

Clive Russell as MacQueen

Michael Cronin as Dr. Lloyd

Max von Sydow as Passenger on Train (Director's Cut) (uncredited)

Roger Frost as Reverend Fisk

Oliver Adams as Gypsy Boy

Emil Hostina as Gypsy Man / Bear Handler

Rick Baker as Gypsy Man / First Killed

Jessica Manley as Gypsy Mother

Jordan Coulson as Wolf Boy

Ian Peck as Creepy Guard

David Keyes as Custodian

C.C. Smiff as Police Officer #3

Anthony Debaeck as Gypsy Driver

Waseem Abbas as Gypsy Boy (uncredited)

Julie Eagleton as Woman in Theatre (uncredited)

Kate Dion-Richard as The Screaming Girl (uncredited)

Salo Gardner as Villager (uncredited)

Andy Gathergood as Villager 1 (uncredited)

Richard Hansell as Asylum Doctor (uncredited)

Sam Hazeldine as Horatio (uncredited)

Mia McKenna-Bruce as Street Urchin (uncredited)

Brigitte Millar as Gertrude (uncredited)

Claude Starling as Asylum Doctor #4 (uncredited)

Karim Theilgaard as Gypsy Man 3 (uncredited)

Christian Wolf-La'Moy as Gentleman in Top Hat (uncredited)

Mario Marin-Borquez as Young Lawrence

Emily Cohen as Little Gypsy Girl

Malcolm Scates as Butcher

Rob Dixon as Squire Strickland

Dave Fisher as Gypsy Man / Stones

Barry McCormick as Asylum Orderly

Shaun Smith as Carter

Richard James as Asylum Doctor #2

Jake Nightingale as Police Officer #2

Debbie Attwell as Gypsy Wife (uncredited)

Piotr Baumann as Gypsy (uncredited)

Peter Paul Burrows as Doctor (uncredited)

Matilda Fulljames as Church Child (uncredited)

Rich Goble as Detective Aberlines Posse (uncredited)

Michael Mansbridge as Musician (uncredited)

David Orpheus as Gypsy (uncredited)

Panayiota Panteli as Gypsy (uncredited)

Emily Parr as Prostitute (uncredited)

Dianne Pilkington as Opera Singer (uncredited)

Robert Roman Ratajczak as Man in the Theatre (uncredited)

Anthony Richard Rowe as Doctor (uncredited)

John Styles as Punch & Judy Man (uncredited)

Branko Tomović as Roman (uncredited)

John Whitby as Detective (uncredited)