Tim Heidecker as Tim Heidecker

Eric Wareheim as Eric Wareheim

John C. Reilly as Taquito

Zach Galifianakis as Jim Joe Kelly

Will Ferrell as Damien Weebs

Robert Loggia as Tommy Schlaaang

Ray Wise as Dr. Doone Struts

Jeff Goldblum as Chef Goldblum

Bob Odenkirk as Schlaaang Announcer (voice)

William Atherton as Earle Swinter

Noah Spencer as Jeffery

Jon Baggio as Jason

Gabriel Bartalos as Wolf Puppeteer

Nancy Stelle as Woman on Paris Street

Ronnie Rodriguez as Diamond Jim / Johnny Depp

Marilyn Porayko as Women Being Ticketed

Andy Spencer as Studio Executive 2

Michael Gross as Narrator

Will Forte as Allan Bishopman

James Quall as Self

David Liebe Hart as Self

Dita de Leon as Cocaine Girl (uncredited)

Bill A. Jones as Serious Announcer

Frank Slaten as Super Seat Customer

Bob Ross as Self

Jean-Michel Richaud as Paris Policeman

Kristopher Logan as Studio Executive 1

Christopher Guckenberger as Studio Executive 3

John Downey III as Cornell

Mary Bly as Mrs. Heidecker

Lillian Adams as Mrs. Wareheim

Jay Mawhinney as Bartender

Loki as Tattoo Artist

Harry Elmayan as Delivery Man

Tennessee Luke as Self

Robert Axelrod as Self

Ted Neubauer as Man on Street

Dena Roe as Woman on Street

Twink Caplan as Katie

Kimberly Ables Jindra as Woman Giving Birth

Kirk Diedrich as Roy

Doug Foster as Customer

Matt O'Toole as Reggie

Rae Sunshine Lee as Shrim God 1

Palmer Scott as Shrim God 2

Mobin Khan as El Hat Propietor

Cole Carl Mangham as Shrim Kid #1

Zachariah James-Jadon Evans as Shrim Kid #2

Frunzik Ayvazyan Jr. as Shrim Kid #3

Joshua Briscoe as Shrim Kid #4

Todd Wagner as Hobo

Howie Slater as Steven Spielberg