Totò as Marc'Antonio / Totonno

Magali Noël as Cleopatra

Moira Orfei as Ottavia

Franco Sportelli as Enobarbo

Lia Zoppelli as Fulvia

Gianni Agus as Ottavio

Toni Ucci as Nasone

Mario Castellani as Il chirurgo cranico reale

Carlo Delle Piane as Cesarione

Adriana Facchetti as Publia

Pietro Carloni as Lepido

Dada Gallotti as Carmiana

Nadia Sanders as Ancella Di Cleopatra

Rossana Canghiari as Schiava (uncredited)

Ignazio Leone as