Dana Snyder as Master Shake (voice)

Carey Means as Frylock (voice)

Dave Willis as Meatwad / Carl / Ignignokt (voice)

Matt Maiellaro as Err / Markula (voice)

Peter Serafinowicz as Neil / Big Neil (voice)

Paul Walter Hauser as Elmer (voice)

Natasha Rothwell as Japongaloid (Japongaloid Natasha) (voice)

Robert Smigel as Fraptaculan (Fraptaculan Robert) (voice)

Tim Robinson as Fraptaculan (Fraptaculan Tim) (voice)

Kyle Kinane as Elric in IT (voice)

Jo Firestone as Felicity in IT (Voice)

Lauren Holt as Liz (voice)

Chris Powell as Stretch Instructor / Japongaloid (Japongaloid Chris) (voice)

Blair Socci as Japongaloid (Japongaloid Blair) (voice)

Shawn Kemp as Shawn Kemp

Lavell Crawford as Street Tough (voice)

John Wilson as Amazin' Board Member (voice)

El-P as Street Tough (voice)

Killer Mike as Boxy Brown (voice)