Geena Davis as Angie Scacciapensieri

Stephen Rea as Noel Riordan

James Gandolfini as Vinnie

Aida Turturro as Tina

Philip Bosco as Frank Scacciapensieri

Jenny O'Hara as Kathy

Michael Rispoli as Jerry

Betty Miller as Joanne

Susan Jaffe as Ballerina

Jeremy Collins as Lover

Robert Conn as Death

Ray Xifo as Dr. Gould

Rosemary De Angelis as Aunt Vicky

Rae Allen as Aunt Violetta

Ida Bernardini as Aunt Louisa

Frank Pellegrino as Uncle Marty

Michael Laskin as Surgeon

Jean Marie Barnwell as Young Angie

Elaine Kagan as Aunt Jean

Olga Merediz as Roz

Marylouise Burke as Fern

Mike Jefferson as Tony

Marin Hinkle as Young Joanne

Nancy Giles as Bedside Nurse

Antoinette Peragine as Circulating Nurse

Charlayne Woodard as Floor Nurse

Adam LeFevre as Museum Guard

Michael Goldfinger as Director

Joanne Baron as ICU Nurse #1

April Grace as ICU Nurse #2

Vernee Watson-Johnson as ICU Desk Nurse

Bibi Osterwald as Dr. Gould's Nurse

Robbie Wenger as Boy in Park

Matt Hofherr as Coffee Shop Waiter

Louis Gigante as Priest

Joanna Sanchez as Admissions Nurse #1

Margaret Cho as Admissions Nurse #2

Anthony Baracco as Tina's Son #1

Leonard Spinelli as Tina's Son #2

John Toles-Bey as Hospital Guard

Eileen Davies as Cranky Labor Nurse

Roseanne Tucci as Bernadette

Maria Venusio as Denise

Marie Coluccio as Nicole

Lauren Cona as Donna

Marya Delia Javier as Alba

Diane DiLascio as Lori

Dawn Hudson as Woman on Bus

James Plair as Bus Driver

Simone Study as Woman at Bar

Ron Michaels as Mechanic #1

Tony Ray Rossi as Mechanic #2

Sharon Claveau as Woman in Window

Marc Allen Lewis as Man in Wheelchair

Lena Banks as Art Museum Patron (uncredited)

Matthew T. Gitkin as Fish Store Assistant (uncredited)

Ash Sroka as Young Tina (uncredited)

Irene Wiley as ICU Nurse (uncredited)