Andy Serkis as Granny / Rastafarian / Hunter Jackson

Hugh Jackman as Roger

Josh Hartnett as The Neighbor

Mary Elizabeth Mastrantonio as Maria

Lyndsey Marshal as Simon's Girlfriend

Sophie Dahl as Veronica

Michael Gambon as Larry

Lynette Curran as Mother

Jason 'Wee Man' Acuña as The Little Man

Jacqui Maxwell as The Beautiful Girl

Joanna Lumley as Last in Line

William Ash as Simon

Nicholas Audsley as Larry's Son

Maureen Lipman as Larry's Wife

Imogen Stubbs as Friend in Crowd

Cate Blanchett as Julie-Anne

Keira Knightley as Leah

Philip Herbert as Paul

Stephen Mangan as David

Naomi Allisstone as Hanna

Amit Lahav as Matt

Valerie Farr as Jane

Bohdan Poraj as Michael

Elizabeth Chadwick as Helen

Paul Bettany as Y

Charlie Condou as X

Tilly Blackwood as Call Girl

Louise Delamere as Woman

Nabil Elouahabi as Barman

James Gandolfini as Vincent

Kathrine Narducci as Carol

Ned Eisenberg as Jimmy

Delilah Cotto as Angela

Daryl Hannah as Herself

Jeff Goldblum as Himself

Sarah Silverman as Herself

Illeana Douglas as Herself

Michael Panes as The Fan

Billy Boyd as The Gunner

Eliza Langland as The Mother

Carmen Pierquaccini as The Intruder