Jackie Chan as Chon Wang

Owen Wilson as Roy O'Bannon

Lucy Liu as Princess Pei Pei

Xander Berkeley as Nathan Van Cleef

Roger Yuan as Lo Fong

Yu Rongguang as Imperial Guard

Walton Goggins as Wallace

Brandon Merrill as Indian Wife

Jason Connery as Andrews

Adrien Dorval as Blue

Stacy Grant as Hooker in Distress

Kate Luyben as Fifi

Henry O as Royal Interpreter

Simon Baker as Little Feather

A.C. Peterson as Saddle Rock Sheriff

Rad Daly as Saddle Rock Deputy

Eliza Norbury as Dream Sequence Hooker

Eric Chen as Imperial Guard

Cui Ya Hui as Imperial Guard

Rafael Báez as Vasquez

Russell Badger as Sioux Chief

Jody Thompson as Margie

Kendall Saunders as Dream Sequence Hooker

Christy Greene as Train Passenger

Yuen Biao as Indian With the Axe / Saloon Fighter (uncredited)

Larry Lam as Railway Worker (uncredited)

Sam Simon as Chief's Sidekick

Olivia Cheng as Dim Sum Girl #1