Denzel Washington as Whip Whitaker

Don Cheadle as Hugh Lang

Kelly Reilly as Nicole

John Goodman as Harling Mays

Bruce Greenwood as Charlie Anderson

Brian Geraghty as Ken Evans

Tamara Tunie as Margaret Thomason

Nadine Velazquez as Katerina Marquez

Peter Gerety as Avington Carr

Garcelle Beauvais as Deana

Melissa Leo as Ellen Block

Carter Cabassa as Son on Plane

Adam C. Edwards as Father on Plane

Conor O'Neill as Kip

Charlie E. Schmidt as Tiki Pot

Will Sherrod as Schecter

Boni Yanagisawa as Camelia Satou

Adam Tomei as Fran

Dane Davenport as Derek Hogue

John Crow as Field Reporter

E. Roger Mitchell as Craig Matson

Ravi Kapoor as Dr. Kenan

Jill Jane Clements as Morning Nurse

Tommy Kane as Mark Mellon

James Badge Dale as Gaunt Young Man

Susie Spear Purcell as Waitress

Philip Pavel as Bartender

Piers Morgan as Piers Morgan

Jim Tilmon as Jim Tilmon

Charles Z. Gardner as Pentecostal Minister

Tom Nowicki as Len Caldwell

Jason Benjamin as Carr's Business Guy / Stalking Reporter

Ric Reitz as Carr's Attorney

Timothy Adams as Whip's Dad

Darius Woods as Young Will

Ron Caldwell as Trevor

Dylan Kussman as Two Beer Barry

Janet Metzger as Sheila

Bethany Anne Lind as Vicky Evans

Sharon Blackwood as Peach Tree Employee

Pam Smith as Peach Tree Employee

Justin Martin as Will Whitaker Jr.

Shannon Walshe as Tilda Banden

Rhoda Griffis as Amanda Anderson

Michael Beasley as Officer Edmonds

Ted Hall as TV Reporter

Laila Pruitt as Girl on Elevator

Precious Bright as Mom on Elevator

Steve Coulter as NTSB Officer at Hearing

Ted Huckabee as Prison Guard

Sarah Clark as Radio Talk Show Host (voice)

Vinnie Hasson as Radio Talk Show Host (voice)

Randy Thom as Radio Stock Market Reporter (voice)

Dennis P. Wise as Air Traffic Controller (voice)

Paul Volle as Air Traffic Controller (voice)

Hal Williams as Whip's Dad (voice)

Kwesi Boakye as Young Will (voice)

Jennifer Olympia Bentley as Naked Girl in Helmet (uncredited)