Rooney Mara as Emily Taylor

Jude Law as Jonathan Banks

Catherine Zeta-Jones as Dr. Victoria Siebert

Channing Tatum as Martin Taylor

Vinessa Shaw as Dierdre Banks

Ann Dowd as Mrs. Taylor

Polly Draper as Eileen Spicer

David Costabile as Carl

Mamie Gummer as Kayla

Scott Shepherd as NYPD Detective

Marin Ireland as Upset Visitor

Elizabeth Rodriguez as Pharmacist

Craig muMs Grant as Wards Island Orderly

Carmen Pelaez as Prison Desk Guard

Peter Friedman as Banks' Partner #1

Laila Robins as Banks Partner #2

Haraldo Alvarez as Garage Attendant

James Martinez as Police Officer at the Hospital

Vladimir Versailles as Augustin

Jacqueline Antaramian as Desk Nurse

Michelle Vergara Moore as Joan

Katie Lowes as Conference Organizer

Steven Platt as Bartender

Victor Cruz as NYPD Officer Beahan

Andrea Bogart as Drug Rep

Mitchell Michaliszyn as Ezra Banks

Elizabeth Rich as Banks Patient #1

Roderick Rodriguez as Paramedic #1

Mark Weekes as Paramedic #2

Michael Nathanson as Assistant District Attorney

Timothy Klein as Transporting Officer Kevin

Sheila Tapia as Emily's Attorney

Josh Elliott as GMA Anchor

Sasha Bardey as Dr. Peter Joubert

Ashley Morrison as Reporter #1

Steve Lacy as Reporter #2

Ken Marks as Banks Patient #2

Devin Ratray as Banks Patient #3

Russell G. Jones as Jeffrey Childs

Munro M. Bonnell as Judge #1

Susan Gross as Susan

Debbie Friedlander as Wards Island Administrator

Ilyana Kadushin as ECT Patient

Johnny Sanchez as ECT Nurse

Nicole Ansari-Cox as Disturbed Patient on Phone

LaChanze as Wards Island Desk Nurse

Alice Niedermair as Wards Island Nurse

Davenia McFadden as Judge

Ray DeBenedictis as Arresting Officer

J. Claude Deering as Zach

Chevy Lamont Cofield as Reporter (uncredited)

Laurence Covington as Wards Island Patient (uncredited)

Barbara Ann Davison as Wards Island Patient (uncredited)

Onika Day as Depressed Woman - Ablixa Commercial (uncredited)

Brian Distance as Wards Medical Staff (uncredited)

John Farrer as Le Circ Restaurant Patron (uncredited)

David Fierro as Wards Island Patient (uncredited)

Rosemary Howard as Prison Visitor (uncredited)

Peter Iasillo Jr. as Inmate (uncredited)

Zivile Kaminskaite as Medical Conference Participant (uncredited)

Peter Y. Kim as Young Stockbroker (uncredited)

Larissa Laurel as Pill Nurse (uncredited)

Sean Marrinan as Pedestrian (uncredited)

Dylan Clark Marshall as Little Boy (uncredited)

Elliott Mayer as Psych Ward Patient (uncredited)

Mario Moise Fontaine as Juror (uncredited)

Nancy Nagrant as Intenin Drug Commercial Mom (uncredited)

Gil O'Brien as Pasta Lover Pedestrian (uncredited)

Kerry O'Malley as Ward Psychiatrist (uncredited)

Greg Paul as Security Guard (uncredited)

Anthony J. Ribustello as Desk Sergeant (uncredited)

Alan R. Rodriguez as Police Officer (uncredited)

Hollie K. Seidel as Depressed Woman - Ablixa Commercial (uncredited)

Kenneth Simmons as Agent (uncredited)

Blago Simon as Fundraiser Guest (uncredited)

Nikky Smedley as Policewoman at Gate (uncredited)

Carol Stanzione as Freaky Poncho Patient (uncredited)

Erica Faye Watson as Processing Nurse (uncredited)

Aaron Roman Weiner as Cop (uncredited)