Clint Eastwood as Gus Lobel

Amy Adams as Mickey Lobel

Justin Timberlake as Johnny Flanagan

Matthew Lillard as Phillip Sanderson

Jack Gilpin as Schwartz

John Goodman as Pete Klein

Robert Patrick as Vince

Scott Eastwood as Billy Clark

Ed Lauter as Max

Chelcie Ross as Smitty

Raymond Anthony Thomas as Lucious

Matt Bush as Danny

George Wyner as Rosenbloom

Bob Gunton as Watson

Tom Dreesen as Rock

James Patrick Freetly as Todd

Joe Massingill as Bo Gentry

Peter Hermann as Greg

Jay Galloway as Rigo Sanchez

Sammy Blue as Musician

Norma Alvarez as Grace Sanchez

Rus Blackwell as Rick

Josh Warren as Pitcher

Seth Meriwether as Wilson

Bart Hansard as Bo's Father

Patricia French as Diner Waitress

Tom Nowicki as Red Sox GM

Julia Walters as Young Mickey

Tyler Silva as Carlos Sanchez

Darren Le Gallo as Nurse

Clayton Landey as Manager

Matthew Brady as Swannanoa Manager

Jackie Prucha as Secretary

Ricky Muse as Jimmy

Carla Fisher as Law Receptionist

Kenny Alfonso as Umpire

Brian F. Durkin as Matt Nelson

Nathan Wright as Drunk Fan

Ryan Patrick Williams as Grizzly Player #1

Xavier Floyd as Grizzly Player #2

Bud Selig as Himself

Cara Mantella as Assistant

Jennifer Baskette-Ridings as News Reporter (uncredited)

Karen Ceesay as Carol (uncredited)

Mark Meekins as Bit

Moses J. Moseley as Baseball Fan (uncredited)

Clifton Guterman as Neil

Sam Collins as Kid #1

Chandler George Brown as Kid #2

Louis Fox as Lloyd

Leon Lamar as Regular #2

Dane Davenport as Waiter #1

Eric Mendenhall as Waiter #2

Melissa Lorenz as Mom in Diner

Rory Lorenz as Girl in Diner

Jack Lorenz as Boy in Diner

Rhubarb Jones as Announcer #2

Scott Estep as Umpire

Jason S. Gondek as Red Sox Exec

Mark Thomason as Braves Official

Hunter Clowdus as Yoga Student (uncredited)