Mark Addy as Fred Flintstone

Stephen Baldwin as Barney Rubble

Kristen Johnston as Wilma Slaghoople

Jane Krakowski as Betty O'Shale

Joan Collins as Pearl Slaghoople

Thomas Gibson as Chip Rockefeller

Alan Cumming as The Great Gazoo / Mick Jagged

Harvey Korman as Colonel Slaghoople

Alex Meneses as Roxie

John Taylor as Keith Richrock

Tony Longo as Big Rocko

Danny Woodburn as Little Rocko

Taylor Negron as Gazaam / Gazing

Jack McGee as Bronto Crane Examiner

David Jean Thomas as Bronto Crane Examiner

Brian Coughlin as Bronto Crane Worker

Richard Karron as Bronto Crane

Jennifer Simard as Bride-To-Be

Heather Simpson as Tennis Girl

Chene Lawson as Kitty

Beverly Sanders as Photographer

John Cho as Parking Valet

Nora Burns as Party Guest

Mark Kubr as Party Guest

Cheryl Holdridge as Genvieve

Buck Kartalian as Old Man at Bronto King

Matt Griesser as Booth Worker

Irwin Keyes as Joe Rockhead

Mary Jo Smith as Gambler Woman

Duane Davis as Goon

Kevin Grevioux as Associate Goon

Steve Schirripa as Croupier

John Wills Martin as Casino Security Guard

Lucille M. Oliver as Hotel Worker

Joel Virgel as Keyboard Player

Rachel Winfree as Confessor

Ted Rooney as Confessor

Jim Doughan as Dinosaur Confessor

Jason Kravits as Choreographer

John Stephenson as Showroom Announcer

Brian Mahoney as Audience Man

Ann Martel Mahoney as Audience Woman

Walter Gertz as Wedding Minister

Mel Blanc as Puppy Dino (voice)

Rosie O'Donnell as Octopus Masseuse (voice)

William Hanna as Special Appearance

Joseph Barbera as Special Appearance

Jennifer Arden as Rockette

Jennifer Bachler as Rockette

Tracie Burton as Rockette

Teresa Chapman as Rockette

Jacqueline Case as Rockette

Betsy Chang as Rockette

Darlene Dillinger as Rockette

Kristen Dinsmore as Rockette

Tracie Hendricks as Rockette

Helena Hultberg as Rockette

Katherine Miller as Rockette

Jessica Page as Rockette

Kim Timbers-Patteri as Rockette

Cristal Williams as Rockette

Kristen Stewart as Ring Toss Girl (uncredited)

Alisa Hensley as Woman at Pool

Janet Dey as Party Guest (uncredited)