Brad Pitt as Mr. O'Brien

Sean Penn as Jack

Jessica Chastain as Mrs. O'Brien

Hunter McCracken as Young Jack

Laramie Eppler as R.L.

Tye Sheridan as Steve

Fiona Shaw as Grandmother

Jessica Fuselier as Guide

Nicolas Gonda as Mr. Reynolds

Will Wallace as Architect

Kelly Koonce as Father Haynes

Bryce Boudoin as Robert

Jimmy Donaldson as Jimmy

Kameron Vaughn as Cayler

Cole Cockburn as Harry Bates

Dustin Allen as George Walsh

Brayden Whisenhunt as Jo Bates

Joanna Going as Jack's Wife

Irene Bedard as Messenger

Michael Koeth as Jack @ 2

Finnegan Williams as Jack @ 5

John Howell as R. L. @ 2

Samantha Martinez as Samantha

Savannah Welch as Mrs. Kimball

Tamara Jolaine as Mrs. Stone

Julia M. Smith as Beth

Anne Nabors as Rue

Christopher Ryan as Prisoner

Tyler Thomas as Tyler Stone

Michael Showers as Mr. Brown

Kimberly Whalen as Mrs. Brown

Margaret Hoard as Jane

Wally Welch as Clergyman

Hudson Lee Long as Mr. Bagley

Michael Dixon as Dusty Walsh

William Hardy as Jack's Work Colleague

Tommy Hollis as Tommy

Cooper Franklin Sutherland as Robert #2

John Cyrier as Bi-Plane Pilot

Erma Lee Alexander as Erma

Nicholas Yedinak as Nicholas Swimmer

Erinn Allison as Mrs. Bates (uncredited)

Mary Anzalone as School Teacher (uncredited)

Charlotte Biggs as 1950s' Woman (uncredited)

Benjamin Dane as Symphony Patron (uncredited)

Michael E. Harvey as Lame Man (uncredited)

Matt Hislope as Clown (uncredited)

Jackson Hurst as Uncle Ray (uncredited)

Zach Irsik as Jack's Son (uncredited)

Scottie Jefferies as Businessman (uncredited)

Gregory Kelly as Prisoner (uncredited)

Carlotta Maggiorana as Ragazza-angelo (uncredited)

Crystal Mantecon as Elisa (uncredited)

Jodie Moore as Mr. Walsh (uncredited)

Kathryn Rawson as Capitol Secretary (uncredited)

Danielle Rene as Woman (uncredited)

Debbi Tucker as Neighbor (uncredited)