Sarah Polley as Ana

Ving Rhames as Kenneth

Jake Weber as Michael

Mekhi Phifer as Andre

Ty Burrell as Steve

Michael Kelly as C.J.

Kevin Zegers as Terry

Michael Barry as Bart

Lindy Booth as Nicole

Jayne Eastwood as Norma

Boyd Banks as Tucker

Inna Korobkina as Luda

R.D. Reid as Glen

Kim Poirier as Monica

Matt Frewer as Frank

Louis Ferreira as Luis

Hannah Lochner as Vivian

Bruce Bohne as Andy

Ermes Blarasin as Bloated Woman

Sanjay Talwar as Doctor Rosen

Kim Roberts as Cora

Tim Post as Reviving Doctor

Matt Sadowski-Austin as EMS Technician

Philip DeWilde as EMS Technician

Colm Magner as Armed Neighbor

Luigia Zucaro as Naked Woman

David Campbel as Squished Zombie

Phillip MacKenzie as Thrashing Zombie

Taso N. Stavrakis as Car Driver (uncredited)

Rorelee Tio as Bus Passenger (uncredited)

Malcolm Scott as Bus Passenger (uncredited)

Ioan Gruffudd as Soldier on Camera (uncredited)

John Migliore as Zombie (uncredited)

Cam Clarke as (voice, uncredited)

Geoff Williams as Metro Bus Driver

Mike Realba as Maintenance Man

David Campbell as Squished Zombie

Laura de Carteret as Washington Politician (as Laura DeCarteret)

Georgia Craig as Anchorwoman

Tino Monte as Istanbul Reporter

Chris Gillett as Older Anchorwoman

Derek Keurvorst as Scientist

Dan Duran as Confused Reporter

Neville Edwards as CDC Spokesperson

Sandy Jobin-Bevans as CDC Reporter

Natalie Brown as CDC Reporter

Liz West as CDC Reporter

Blu as Chips the Dog

Scott H. Reiniger as The General (as Scott Reiniger)

Tom Savini as The County Sheriff

Ken Foree as The Televangelist

Darren Marsman as Maintenance Man Zombie (uncredited)

Zack Snyder as Commando at White House (uncredited)