Jessica Biel as Erin Hardesty

Jonathan Tucker as Morgan

Andrew Bryniarski as Thomas Hewitt / Leatherface

Erica Leerhsen as Pepper

Eric Balfour as Kemper

Mike Vogel as Andy

R. Lee Ermey as Sheriff Hoyt

David Dorfman as Jedidiah

Lauren German as The Hitchhiker

Heather Kafka as Henrietta

Terrence Evans as Monty Hewitt

Marietta Marich as Luda Mae Hewitt

John Larroquette as Narrator (voice)

Kathy Lamkin as Tea Lady in Trailer

Brad Leland as Big Rig Bob

Mamie Meek as Clerk

Harry Jay Knowles as Victim On a Silver Platter (uncredited)

Scott Martin Gershin as Leatherface (voice) (uncredited)