Malcolm McDowell as Dr. Samuel Loomis

Sheri Moon Zombie as Deborah Myers

Tyler Mane as Michael Myers

Scout Taylor-Compton as Laurie Strode

Brad Dourif as Sheriff Lee Brackett

Danielle Harris as Annie Brackett

Hanna Hall as Judith Myers

Daeg Faerch as Michael Myers, Age 10

Kristina Klebe as Lynda

Danny Trejo as Ismael Cruz

Ken Foree as Big Joe Grizzly

Udo Kier as Morgan Walker

Sid Haig as Chester Chesterfield

Daryl Sabara as Wesley Rhoades

Daniel Roebuck as Lou Martini

Richard Lynch as Principal Chambers

William Forsythe as Ronnie White

Clint Howard as Doctor Koplenson

Lew Temple as Noel Kluggs

Tom Towles as Larry Redgrave

Bill Moseley as Zach "Z-Man" Garrett

Leslie Easterbrook as Patty Frost

Steve Boyles as Stan Payne

Skyler Gisondo as Tommy Doyal

Jenny Gregg Stewart as Lindsey Wallace

Adam Weisman as Steve

Sydnie Pitzer as Baby Boo

Myla Pitzer as Baby Boo

Stella Altman as Baby Boo

Dee Wallace as Cynthia Strode

Max Van Ville as Paul

Nick Mennell as Bob Simms

Pat Skipper as Mason Strode

Richmond Arquette as Deputy Charles

Paul Kampf as Officer Lowery

Sybil Danning as Nurse Wynn

Micky Dolenz as Derek Allen

Mel Fair as Taylor Madison

Nikki Taylor Melton as Princess

Deven Streeton as Princess

Andreana Weiner as Voice Performer (voice)

David Michie as Voice Performer (voice)

Paige Pollack as Voice Performer (voice)

Jeremy Maxwell as Voice Performer (voice)

Barbara Harris as Voice Performer (voice)

David J. Randolph as Voice Performer (voice)

Noreen Reardon as Voice Performer (voice)

John DeMita as Voice Performer (voice)

Nancy Truman as Voice Performer (voice)

Daamen J. Krall as Voice Performer (voice)

Courtney Gains as Jack Kendall (uncredited)

Ezra Buzzington as Graveyard Keeper (uncredited)

Gary Grossman as Drunk "Rabbit in Red" Patron (uncredited)

Kazu Nagahama as College Student (uncredited)

Olja Hrustic as Raped Inmate (uncredited)

Richard Fancy as University Dean (uncredited)