Malcolm McDowell as Dr. Samuel Loomis

Sheri Moon Zombie as Deborah Myers

William Forsythe as Ronnie White

Tyler Mane as Michael Myers

Scout Taylor-Compton as Laurie Strode

Brad Dourif as Sheriff Leigh Brackett

Danielle Harris as Annie Brackett

Hanna Hall as Judith Myers

Bill Moseley as Zach 'Z-Man' Garrett

Daeg Faerch as Michael Myers, Age 10

Kristina Klebe as Lynda van der Klok

Danny Trejo as Ismael Cruz

Ken Foree as Big Joe Grizzly

Udo Kier as Morgan Walker

Sid Haig as Chester Chesterfield

Daryl Sabara as Wesley Rhoades

Daniel Roebuck as Lou Martini

Richard Lynch as Principal Chambers

Clint Howard as Doctor Koplenson

Lew Temple as Noel Kluggs

Tom Towles as Larry Redgrave

Leslie Easterbrook as Patty Frost

Steve Boyles as Stan Payne

Skyler Gisondo as Tommy Doyle

Jenny Gregg Stewart as Lindsey Wallace

Adam Weisman as Steve Haley

Sydnie Pitzer as Baby Boo

Myla Pitzer as Baby Boo

Stella Altman as Baby Boo

Dee Wallace as Cynthia Strode

Max Van Ville as Paul

Nick Mennell as Bob Simms

Pat Skipper as Mason Strode

Richmond Arquette as Deputy Charles

Paul Kampf as Officer Lowery

Sybil Danning as Nurse Wynn

Micky Dolenz as Derek Allen

Mel Fair as Taylor Madison

Nikki Taylor Melton as Princess

Deven Streeton as Princess

Ezra Buzzington as Graveyard Keeper (uncredited)

Richard Fancy as University Dean (uncredited)

Courtney Gains as Jack Kendall (uncredited)

Gary Grossman as Drunk 'Rabbit in Red' Patron (uncredited)

Olja Hrustic as Raped Inmate (uncredited)

Kazu Nagahama as College Student #3 (uncredited)