Clint Eastwood as Manco

Lee Van Cleef as Col. Douglas Mortimer

Gian Maria Volonté as El Indio

Luigi Pistilli as Groggy, Member of Indio's Gang

Klaus Kinski as Juan Wild - The Hunchback

Joseph Egger as Old Prophet

Panos Papadopulos as Sancho Perez, Member of Indio's Gang

Mara Krupp as Mary

Benito Stefanelli as Luke 'Hughie'

Roberto Camardiel as Tucumcari Station Clerk

Aldo Sambrell as Cuchillo

Luis Rodríguez as Manuel, Member of Indio's Gang

Tomás Blanco as Tucumcari Sheriff

Lorenzo Robledo as Tomaso, Indio's Traitor

Sergio Mendizábal as Tucumcari Bank Manager

Dante Maggio as Carpenter in Cell with El Indio

Diana Rabito as Callaway's Beautiful Girl in Tub

Giovanni Tarallo as Santa Cruz Telegraphist

Mario Meniconi as Train Conductor

Mario Brega as Niño, Member of Indio's Gang

José Terrón as Guy Calloway, Mortimer's 1st Criminal (uncredited)

José Marco as 'Baby' Red Cavanaugh (uncredited)

Werner Abrolat as Slim, Member of Indio's Gang (uncredited)

Frank Braña as Blackie, Member of Indio's Gang (uncredited)

José Canalejas as Chico, Member of Indio's Gang (uncredited)

Antonio Molino Rojo as Frisco, Member of Indio's Gang (uncredited)

Jesús Guzmán as Carpetbagger on Train (uncredited)

Ricardo Palacios as Tucumcari Saloon Keeper (uncredited)

Guillermo Méndez as White Rocks Sheriff (uncredited)

Rosemary Dexter as Mortimer's Sister (uncredited)

Peter Lee Lawrence as Mortimer's Brother-in-Law (uncredited)

Kurt Zips as Hotel Manager (uncredited)

Enrique Navarro as (uncredited)

Bruno Corazzari as Poker Player (uncredited)

Carlo Simi as El Paso Bank Manager (uncredited)

Antoñito Ruiz as Fernando (uncredited)

Román Ariznavarreta as Half-Shaved Bounty Hunter (uncredited)

Joseph Bradley as El Paso Tavern Keeper (uncredited)

Fernando Di Leo as Cigar Smoking Card Player (uncredited)

Diana Faenza as Tomaso's Wife (uncredited)

Eduardo García as Member of Indio's Gang (uncredited)

Maurizio Graf as The Balladeer (voice) (uncredited)

Francesca Leone as Tomaso's Baby (uncredited)

Sergio Leone as Whistling Bounty Hunter (voice) (uncredited)

Rafael López as (uncredited)

Antonio Palombi as Bartender (uncredited)

Aldo Ricci as (uncredited)

Enrique Santiago as Miguel, Member of Indio's Gang (uncredited)

Edmondo Tieghi as 2nd Agua Caliente Villager Watching Monco (uncredited)

Antonio Montoya as Paco, Member of Indio's Gang (as José Montoya)