E. G. Daily as Babe (voice)

Magda Szubanski as Mrs. Esme Cordelia Hoggett

James Cromwell as Farmer Arthur Hoggett

Mickey Rooney as Fugly Floom, the Speechless Man in Hotel

Mary Stein as Miss Floom

Danny Mann as Ferdinand / Tug / Additional Character Voices (voice)

Glenne Headly as Zootie (voice)

Steven Wright as Bob (voice)

James Cosmo as Thelonius (voice)

Nathan Kress as Easy / Tough Pup (voice)

Myles Jeffrey as Easy (voice)

Julie Godfrey as Hortense

Janet Foye as Mrs. Hoggett's Friend

Pamela Hawkins as Miss Hogget's friend

Paul Livingston as Chef

Kim Story as Judge

John Upton as Boy

Stanley Ralph Ross as The Bull Terrier / The Doberman (voice)

Russi Taylor as The Pink Poodle / Choir Cat (voice)

Adam Goldberg as Flealick (voice)

Eddie Barth as Nigel / Alan (voice)

Bill Capizzi as Snoop, The Sniffer Dog (voice)

Miriam Margolyes as Fly (voice)

Hugo Weaving as Rex (voice)

Jim Cummings as Pelican (voice)

Katie Leigh as Kitten (voice)

Evelyn Krape as Sheep / Cat (voice)

Charles Bartlett as Cow (voice)

Michael Edward-Stevens as Horse (voice)

Al Mancini as Fish (voice)

Larry Moss as Fish (voice)

Roscoe Lee Browne as The Narrator (voice)

Lisa Bailey as Additional Character Voices (voice)

Balyne Barbosa as Additional Character Voices (voice)

Victor Brandt as Additional Character Voices (voice)

Jeannie Elias as Additional Character Voices (voice)

Pippa Grandison as Additional Character Voices (voice)

Mark Hammond as Additional Character Voices (voice)

J.D. Hall as Additional Character Voices (voice)

Wendy Hammers as Additional Character Voices (voice)

Scotty Leavenworth as Additional Character Voices (voice)

Julie Oppenheimer as Additional Character Voices (voice)

Deborah Packer as Additional Character Voices (voice)

Roger Rose as Additional Character Voices (voice)

Carly Schroeder as Additional Character Voices (voice)

Joseph R. Sicari as Additional Character Voices (voice)

Aaron Spann as Additional Character Voices (voice)

Drew Lexi Thomas as Additional Character Voices (voice)

Naomi Watts as Additional Character Voices (voice)

Christian Manon as Lab Technician

Richard Huggett as Cop

Cecelia Yates as Flight Attendant

Damian Monk as Customs Guard

Anthony Phelan as Security Guard

Basil Clarke as Doctor

Richard Carter as Detective

Barbara Harris as Additional Character Voices (voice)

Dominic Condon as Kitchen Hand