Mckenna Grace as Phoebe Spengler

Paul Rudd as Gary Grooberson

Carrie Coon as Callie Spengler

Finn Wolfhard as Trevor Spengler

Dan Aykroyd as Ray Stantz

Kumail Nanjiani as Nadeem

Patton Oswalt as Dr. Hubert Wartzki

Celeste O'Connor as Lucky

Logan Kim as Podcast

Emily Alyn Lind as Melody

James Acaster as Lars

Bill Murray as Peter Venkman

Ernie Hudson as Winston Zeddemore

Annie Potts as Janine Melnitz

William Atherton as Mayor Walter Peck

Shelley Williams as Senior Advisor

Chris Tummings as Police Chief

John Rothman as Library Administrator

Stephen Whitfield as Fire Captain (1904)

Samuel Greco as Firefighter (1904)

Chris Ginesi as Firefighter (1904)

Brandon Burke as Firefighter (1904)

Karack Osborn as Firefighter (1904)

Kevin Mangold as Slimer (Puppeteer)

Ian Whyte as Garraka (Puppeteer)

Natalie Cousteau as Dadi

Allison McKay as Ms. Mikowski

Adam Speers as Doll Owner

Claire Titelman as News Correspondent

Kalisha Amaris Johnson as Reporter

Evelyn Edwards as Reporter

Andrew Goddard as Reporter

Deeivya Meir as Reporter

Sophia Lucia Parola as Woman (Beach)

Megan Robinson as Mother (Coffee Shop)

Evelyn Anne Bulls as Child (Coffee Shop)

Camari Brown as Man Running Away (Beach)

Claudia Nell McCoy as Woman Running Away (Beach)

Damian Muziani as Taxi Driver (In Traffic)

Remy Germinario as Tourist Couple Looking at Map

Michael Kushner as Tourist Couple Looking at Map

Deisy Patiño as Woman's Friend at Beach

Victoria Giler as Woman's Friend at Beach

Cassidy Goron as Child (Beach)

Georgia Arron as Podcast's Fan

Jesse Gallegos as Vape Shop Clerk

Jonathan Mercedes as NY Cop

Vinnie Coppola as NY Cop

A.J. Voliton as NYC Bystander

Adam Murray as Truck Driver

Pat Kiernan as News Anchor

Shelby Young as Mini-Pufts (voice) (uncredited)

Ryan Bartley as Mini-Pufts (voice) (uncredited)

Bella Glanville as Influencer (uncredited)

Maria Teresa Creasey as Waitress