Mckenna Grace as Phoebe Spengler

Finn Wolfhard as Trevor Spengler

Carrie Coon as Callie Spengler

Bokeem Woodbine as Sheriff Domingo

Paul Rudd as Gary Grooberson

Logan Kim as Podcast

Celeste O'Connor as Lucky

Bill Murray as Peter Venkman

Dan Aykroyd as Ray Stantz

Ernie Hudson as Winston Zeddemore

Annie Potts as Janine Melnitz

Sigourney Weaver as Dana Barrett

Bob Gunton as The Ghost Farmer

J.K. Simmons as Ivo Shandor

Shawn Seward as Skittles

Billy Bryk as Zahk

Sydney Mae Diaz as Swayze

Hannah Duke as Reseda

Paulina Alexis as Bunny

Marlon Kazadi as Thick Neck

Chiara Petersen as Burner Girl

Danielle Kennedy as Roller Granny

Artoun Nazareth as Rufus

Crystal Roseborough as Crystal

Dusan Rokvic as Landlord

Emma Portner as Spirit of Gozer

Stella Aykroyd as Deputy Medjuck

Kim Faires as Waitress

Josh Gad as Muncher (voice)

Shohreh Aghdashloo as Gozer (voice)

Tracy Letts as Jack (uncredited)

Olivia Wilde as Gozer the Gozerian (uncredited)

Harold Ramis as Dr. Egon Spengler (archive footage) (uncredited)

Oliver Cooper as Elton (uncredited)

CJ Collard as Diner Patron (uncredited)

Bud Klasky as Sheriff / Restaurant (uncredited)

Faith Louissaint as Diner Counter Staff (uncredited)

Daniel D'Angelo Sparks as Walmart Customer (uncredited)

Ira Heiden as Mini Stay-Puft Marshmallow Men (voice) (uncredited)

Sarah Natochenny as Mini Stay-Puft Marshmallow Men (voice) (uncredited)