Misha Collins as Paul Bernardo

Laura Prepon as Karla Homolka

Brandon Routh as Tim

Patrick Bauchau as Dr. Arnold

Emilie Jacobs as Debbie

Adam Lieberman as Detective Morgan

Shawn Hoffman as Detective Steve Kirby

William Duffy as Detective Porter

Alex Boyd as Nick

Cherilyn Hayres as Tammy Homolka

Kristen Honey as Tina McCarthy (as Kristen Swieconek)

Cole James as Tina's Friend

Carole Ita White as Waitress

Fiona Manners as Rape Victim #1

Tanya Lemelle as Rape Victim #2

Tony Shawkat as Border Guard #1