Sylvester Stallone as Lieutenant Marion 'Cobra' Cobretti

Brigitte Nielsen as Ingrid

Reni Santoni as Sergeant Gonzales

Brian Thompson as Night Slasher

Lee Garlington as Nancy Stalk

Art LaFleur as Captain Sears

Andrew Robinson as Detective Monte

Marco Rodríguez as Supermarket Killer

Val Avery as Chief Halliwell

Nina Axelrod as Waitress

David Rasche as Dan

John Herzfeld as Cho

Ross St. Phillip as Security Guard

John Hauk as Low Rider

Nick Angotti as Prodski

Brad Bovee as Innocent Bystander

Kevin Breslin as Supermarket Kid

Roger Aaron Brown as Policeman #2

John Cahill as Father of Blonde Girl

Louise Caire Clark as Woman in Car

Christine Craft as TV News Reporter

Gregory Cruz as Janitor (as Gregory Norman Cruz)

Deborah Dalton as Nurse #2

Scott Dockstader as Killer #2

Laura Drake as Murdered Waitress

Karen Kondazian as Nurse

Dorothy Meyer as Nurse #1

Clare Torao as Reporter #2 (as Clare Nono)

Julie Hampton as Policewoman (uncredited)

Helen Kelly as News Reporter #8 (uncredited)

Ron Jeremy as Extra (uncredited)

Bert Williams as Commissioner Reddesdale

Joe Bonny as Policeman #1