Andy Samberg as Rod Kimble

Jorma Taccone as Kevin Powell

Bill Hader as Dave

Danny McBride as Rico

Isla Fisher as Denise

Sissy Spacek as Marie Powell

Ian McShane as Frank Powell

Will Arnett as Jonathan

Chris Parnell as Barry Pasternack

Chester Tam as Richardson

Mark Acheson as Homeless Dude

Brittany Tiplady as Maggie

Ken Kirzinger as Trailer Guy

Britt Irvin as Cathy

Alana Husband as Waitress

Andrew Moxham as Sullivan

Terri O'Neill as Angry Mom

Alvin Sanders as Furious Boss

Chris Eastman as EMT

Paulo Ribeiro as EMT

Paul Herbert as EMT

Carly McKillip as High School Girl

Donavon Stinson as Heckler

John Destry as Projectionist

Doug Abrahams as Police Officer

Frank C. Turner as Fisherman

Henry Michaels as Boy Stealing Wheelchair

Gillian Barber as Riot Singer

Sammy Fattedad as Riot Singer

William S. Taylor as Riot Singer

Mi-Jung Lee as Newswoman

Carrie Ruscheinsky as Hippie Girl

Charlie Hope as Autograph Kid

Matthew Gallagher as Autograph Kid

Viktoria Kampbell as Autograph Kid

Titan Toyish as "Gown"

Joshua Homme as "Gown"

Joseph Castillo as "Gown"

Alain Moschulski as "Gown"

Troy Van Leeuwen as "Gown"

Jesse Haddock as Crowd Member

Ometa Gittens as Crowd Member

Aaron Au as Taco

Brett Chan as Grilled Cheese

John Burnside as Scrooge

Akiva Schaffer as Derrick (uncredited)

Stephen Altman as Rod's Dad (uncredited)

Ryan Hess as Construction Worker (uncredited)

Meghan K. Lees as Cheer Girl (uncredited)

Jennifer LaPlaca as Cashier (uncredited)

Elizabeth McCarthy as Grocery Store Mom (uncredited)

Patricia Schaffer as Woman with Grocery Bags Dodging Flyers (uncredited)

Tom MacNeill as Crowd Member (uncredited)

Marjorie Roden as Crowd Member (uncredited)