Leonardo DiCaprio as Bob

Sean Penn as Col. Steven J. Lockjaw

Chase Infiniti as Willa

Benicio del Toro as Sensei Sergio St. Carlos

Regina Hall as Deandra

Teyana Taylor as Perfidia

Wood Harris as Laredo

Tony Goldwyn as Virgil Throckmorton

D.W. Moffett as Bill Desmond

Paul Grimstad as Sommerville

Dijon as Talleyrand

Kevin Tighe as Roy More

John Hoogenakker as Tim Smith

Eric Schweig as Avanti

April Grace as Sister Rochelle

Jim Downey as Sandy Irvine

Alana Haim as Mae West

Shayna McHayle as Junglepussy

Brooklyn Demme as Sober Rick

Sachi Diserafino as R.A. Rippey

Melissa Dueñas as Sylvia

Starletta DuPois as Grandma Minnie

Vanessa Ganter as Momma Sandrae

Otillia Gupta as Newborn Baby Charlene

Nia Leon as Baby Charlene

Peter N. Lyas III as Bank Security Guard

Joe Silva as Sgt. Joe

Jeffrey Massagli as Official Lockjaw Award

Nicole J. Sunseri as Witness Protection Officer

Tisha Sloan as Willa's Teacher

Alberto Garcia as Snap Crackle Pop Kid

Antonio Tadeo Garcia as Snap Crackle Pop Kid

Patricia Ridgely-Storm as Alice More

Ted McCarthy as Christmas Ted

Jeremy Boone as CAC Security

James Raterman as Danvers

Bryan Pickens as Billy Toejam

Travis Johnston as Soldier

Matthew Demildt as Soldier

Jason Belford as Soldier

Matthew McDonnell as Soldier

Jose L Barreiro as Soldier

Quentin L. Carter as Soldier

Brian Bishop as Soldier

Daniel Zinoviev as Soldier

Steven Knoll as Military Man

Sam Hunter as Military Man

Louis Hoffman as Military Man

Steven P. Jacobson as Military Man

Justin Millmore as Military Man

Peter Sutherland as Military Man

Carlos McFarland as Bluto

Colton Gantt as Bobo

Elisabeth Pease as RiRi

Autumn Crosswhite as Autumn

Mickey Giacomazzi as Deandra's Van Driver

Omar Khattab as Principal

Stephanie Coker Aderonokun as Bathroom Girl

Kayla Harvey as Bathroom Girl

Kimberlyn Ramirez Moreno as Bathroom Girl

Sydney Ann Taylor as Bathroom Girl

Maria Fernanda Jimenez Nava as Bathroom Girl

Jena Malone as Greeting Code (voice)

Dan Chariton as Comrade Josh

Sandra Iturbe as Reina

Marisela Borjas Ramirez as Marisela

Derrick J. Saenz as Primo Derrick

Esperanza Rodarte De Santoyo as Esperanza

Hadasa Genesaret Palomares as Sacred Heart

Gilberto Martinez Jr. as BeeGee

Luis Trejo as Luis

Julian Corral as Julian

Elijah Joseph Sambrano as Latino Heat

Sherron Gassoway as Sister Vox

Pearl Minnie Anderson as Sister Coco

Sister Kate as Sister

Sister Halla as Sister

Sister Lilly as Sister

Sister Esme as Sister

Sister Karina as Sister

Sister Laura as Sister

Sister Delphi as Sister

Sister Yuka as Sister

Bella Feinstein as Sister

Madison Feinstein as Sister

Tuesday Hansen as Sister

Zoe Herschlag as Sister

J. Izon as Sister

Joanna Scott Satterwhite as Sister

Robert Sherock as Paddy Wagon Cop

Lynette M. Telles as Police Station Nurse

Pamela Limbaugh-Brouhard as Hospital Nurse

Antonio Garcia as Tacos T-Shirt

Emilio Carranza as Fruit Stand Tio

Juan V. Ramirez as Fruit Stand Primo

Ron Bermudez Perea as Fruit Stand Primo

Edith Ascencion as Sensei Sheriff

David Reynoso as Sensei Sheriff

Timothy Cruz Kravitz as 1776 Relentless

Jon Beavers as 1776 James

Anthony Weise as CB Radio