George Clooney as Jay Kelly

Adam Sandler as Ron Sukenick

Laura Dern as Liz

Billy Crudup as Timothy

Riley Keough as Jessica Kelly

Grace Edwards as Daisy Kelly

Stacy Keach as Jay's Dad

Jim Broadbent as Peter Schneider

Patrick Wilson as Ben Alcock

Eve Hewson as Daphne

Greta Gerwig as Lois Sukenick

Alba Rohrwacher as Alba

Josh Hamilton as Carter

Lenny Henry as Larry

Emily Mortimer as Candy

Nicôle Lecky as Krista

Thaddea Graham as Meg

Isla Fisher as Melanie Alcock

Stanley Townsend as First Voice (voice)

Erica Sweany as Costume Designer

Kevin Shen as 2nd AD

David Neumann as Sound Recordist

Leila Farzad as 1st AD

Juliet Cowan as Actress

Eleanor Matsuura as Dresser

Lucas Aurelio as Electrician

Tuwaine Barrett as Rain Rigger

Martha West as Set PA

Philip Arditti as Cinematographer

Nigel Whitmey as Stand-in

Kyle Soller as Director

Parker Sawyers as Props

Giovanni Zeqireya as Silvano

Doug Cockle as Nathan

Sadie Sandler as Vivienne Sukenick

Helene Maksoud as Mourner

Dean Wareham as Mourner

Ruthie Rogers as Mourner

Josh Berger as Mourner

Penny Mortimer as Mourner

Christine Crais as College Kid at Bar

Kwabena Peprah as College Kid at Bar

Carlos Jacott as Gordon

Eloise Jacott as Michelle

John Macmillan as Chef

Andreas Muñoz as Chef Mario

Lars Eidinger as German Cyclist

Ferdi Stofmeel as Dutch Cyclist

Rosita Raffaelli as Daisy Lookalike

Antoinette Aaron as French Fan

Philippe Spall as Train Conductor

Nasser Memarzia as Professor

Christophe Guybet as French Businessman

Annabel Mullion as Woman in the Window

Federico Scribani as Fireman

Francesco De Vito as Farm Equipment

Sharon Rooney as Backpacker

Hannah Onslow as Backpacker

Amber Mendez Martin as Backpacker

Janine Duvitski as Sharon

Jamie Demetriou as Clive

Patsy Ferran as Brenda

Pippo Crotti as Priest

Yinka Awoni as Priest

May Nivola as Phoebe

Théo Augier as Guillaume

Alex Jarrett as Rio

Alaïs Lawson as Daisy's Friend

Cassius Hackforth as Daisy's Friend

Emily Piggford as Captain Jenny

Danielle Lewis as Co-Pilot Lourdes

Giovanni Esposito as Antonio

Monica Nappo as Catherina

Galatea Ranzi as Camilla

Fabio Vannozzi as Giovanni

Arianna Becheroni as Isabella

Lucian St Aubyn as Zeke

Marco Conte as Doctor

Donald Sabourin as Brother-in-Law Spike

Matilda Thorpe as Barbara

Charlie Rowe as Young Jay Kelly

Louis Partridge as Young Timothy

Ruby Stokes as Sara

Alastair Coughlan as Actor at Audition

Andrew Malik as Actor at Audition

Joe Hewetson as Actor at Audition

Max Beken as Actor at Audition

Tom Francis as Actor at Audition

Carly-Sophia Davies as Casting Assistant

Debora Weston as Casting Director

Martin McDougall as 1st AD

Kit Rakusen as Eli

Sadie Stallcup as Young Daisy

Noah Baumbach as Director (uncredited)

Phạm Quang Minh as Kak