Bill Hader as Flint Lockwood (voice)

Anna Faris as Sam Sparks (voice)

James Caan as Tim Lockwood (voice)

Will Forte as Chester V (voice)

Andy Samberg as Brent McHale (voice)

Benjamin Bratt as Manny (voice)

Neil Patrick Harris as Steve (voice)

Terry Crews as Earl Devereaux (voice)

Kristen Schaal as Barb (voice)

Cody Cameron as Barry / Dill Pickle (voice)

Melissa Sturm as Sentinel Louise / Live Corp Scientist (voice)

Kris Pearn as Sentinel Peter / Labcoat Jenny (voice)

Craig Kellman as Fintly McCallahan / Idea Pants Guy (voice)

Khamani Griffin as Cal Devereaux (voice)

Bridget Hoffman as Young Flint (voice)

Al Roker as Patrick Patrickson (voice)

Steve Alterman as Additional Voices (voice)

June Christopher as Additional Voices (voice)

David Cowgill as Additional Voices (voice)

Eddie Frierson as Additional Voices (voice)

Elisa Gabrielli as Additional Voices (voice)

Jackie Gonneau as Additional Voices (voice)

Tania Gunadi as Additional Voices (voice)

Wendy Hoffmann as Additional Voices (voice)

Walter Jones as Additional Voices (voice)

Ashley Lambert as Additional Voices (voice)

Scott Menville as Additional Voices (voice)

David Sheinkopf as Additional Voices (voice)

Peter Siragusa as Additional Voices (voice)

Marina Squerciati as Additional Voices (voice)

Kelly Stables as Additional Voices (voice)

Shane Sweet as Additional Voices (voice)

Maddie Taylor as Additional Voices (voice)