Selma Blair as Rigby

Christina Ricci as Rebecca

Courteney Cox as Beth

Susan Sarandon as Millie

Eva Amurri as Gayle

Sharon Stone as Nina

Mira Sorvino as Georgina Scott

Paul Wesley as Kevin

Luke Mitchell as Nelson Quinn

Paul Adelstein as Peter

Natalie Burn as Young Lydia

Quinton Aaron as Dr. Hamilton

Ashanti as Kelly

Liana Mendoza as Grace

E. G. Daily as Momma Quinn

Julia Lanski as Anastasia

Maria Gabriela Cardenas as Girl at Club

Gilles Marini as Bill

Christopher Backus as Sebastien

Luke Sanson as Jake

Steven Scot Bono as Seamus

Sebastian Siegel as Billy

Alexandra Daniels as Layla

Stephanie Shamie as Tricia

David Kloehr as Tony

Vic Stagliano as Mike

Dave Baez as Dr. Conrad

Danielle James as Dr. Jill Barnard

Steph LeHane as Concertgoer