Drew Barrymore as Sophie Fisher

Hugh Grant as Alex Fletcher

Toni Trucks as Tricia

Brad Garrett as Chris Riley

Haley Bennett as Cora Corman

Brooke Tansley as Janice Stern

Aasif Mandvi as Khan

Zak Orth as David Newbert

Scott Porter as Colin Thompson

Nick Bacon as Pop Bass Player

Andrew Wyatt as Pop Guitar Player

Dan McMillan as Pop Drummer

Tom Foligno as Has-Beens Promo Announcer (voice)

Daniel Stewart Sherman as Willy

Matthew Morrison as Ray

Jason Antoon as Greg Antonsky

Jeremy Karson as Charlie

Emma Lesser as Lucy

Kristen Johnston as Rhonda

Adam Grupper as Gary

Charlotte Maier as Barbara

Lanette Ware as Mia

Campbell Scott as Sloan Cates

Billy Griffith as Derek

Kathleen McNenny as Gloria

Stevie Ray Dallimore as Maitre d'

Spenser Leigh as Beth Riley

Lou Torres as Security Guard

Kali R. Harrison as Stage Manager

Dan Karaty as Choreographer

Chris Moss as Dancer

Christine Ashley DeJesus as Dancer

Dana DePalo as Dancer

Gerard Heintz as Dancer

Antoine 'Doc' Judkins as Dancer

Nick Kenkel as Dancer

Nina Lafarga as Dancer

Carly Lang as Dancer

Monique Lea-Gall as Dancer

Sarah Mitchell as Dancer

Marielys Molina as Dancer

Jorge Santos as Dancer

Seth Stewart as Dancer

Roel Suasin as Dancer

Reed Kelly as Dancer

Ariana Bernstein as Girl at Concert (uncredited)

Bill Chemerka as Concert Vendor (uncredited)

Michael Ciesla as Party Guest (uncredited)

Peter Conboy as Reunion Classmate (uncredited)

Jeannine Kaspar as Girlfriend of Alex Fletcher (uncredited)

Mark A. Keeton as Sloan's Dinner Companion (uncredited)

Bernadette Lords as Cora Corman Fan (uncredited)

Suzi Lorraine as Nurse (uncredited)

Robert Sciglimpaglia as Reunion Classmate (uncredited)

Carlos Velazquez as Waiter (uncredited)