Hugh Grant as Martin Tweed

Dennis Quaid as President Staton

Mandy Moore as Sally Kendoo

Willem Dafoe as Chief of Staff

Chris Klein as William Williams

Jennifer Coolidge as Martha Kendoo

Sam Golzari as Omer

Marcia Gay Harden as First Lady

Seth Meyers as Chet Krogl

John Cho as Ittles

Judy Greer as Accordo

Bernard White as Agha Babur

Tony Yalda as Iqbal Riza

Noureen DeWulf as Shazzy Riza

Shohreh Aghdashloo as Nazneen Riza

Marley Shelton as Jessica

Lisa K. Wyatt as Aunt Edna

Beau Holden as Uncle Fitz

Jay Harik as Ali Riza

Adam Busch as Sholem Glickstein

Haaz Sleiman as Mujeheddin Captain

Nicholas Schutt as Cameraman

Lawrence Pressman as White House Butler

Aldis Hodge as Soldier Chuck

Tim Rhoze as Stage Manager

Christianne Klein as White House Reporter

Chao-Li Chi as Chinese Premiere

Andrew Divoff as Chinese Translator

Perrey Reeves as Marni

Carmen Electra as Herself

Karen-Eileen Gordon as Sally's Makeup Artist

Daniel Weiss as Man in Line

James Gleason as Journalist

Michael D. Roberts as Journalist

Kevin R. Kelly as Journalist

Mike Batayeh as Terrorist Director

Joshua Wade as Show Contestant

Niki J. Crawford as Show Contestant

Trey Parker as Show Contestant

Samantha Jade as Show Contestant

John Griffin as Show Contestant

Danny Ehrhardt as Montage Performer

Sarah Culberson as Montage Performer

Kevin Makely as Secret Service Man

Jeff Ross as Oscar

Bruce Garrick as Crew Member

P.D. Mani as Cohort

Wally Lozano as Terrorist (uncredited)

John D. Crawford as Studio Security