Frank Welker as Scooby-Doo / Fred Jones (voice)

Casey Kasem as Shaggy Rogers (voice)

Grey DeLisle as Daphne Blake / Cat Witch / Honeybee (voice)

Mindy Cohn as Velma Dinkley (voice)

Lauren Bacall as The Grand Witch (voice)

Tim Curry as The Goblin King (voice)

Jim Belushi as Glob (voice)

Wayne Knight as The Amazing Krudsky (voice)

Wallace Shawn as Mr. Gibbles (voice)

Hayden Panettiere as Fairy Princess Willow (voice)

Larry Joe Campbell as Glum (voice)

Jay Leno as Jack O'Lantern (voice)

Thom Adcox-Hernandez as Sparkplug (voice)

Russi Taylor as Owl Witch / Tiddlywink (voice)