Frank Welker as Scooby-Doo / Fred Jones (voice)

Mindy Cohn as Velma Dinkley (voice)

Grey DeLisle as Daphne Blake (voice)

Matthew Lillard as Shaggy Rogers (voice)

Gabriel Iglesias as Professor Perez (voice)

Carlos Alazraqui as Brazillian Player (voice)

Andrew Kishino as Security Guard (voice)

Rob Paulsen as Julio (voice)

Danny Trejo as Reynaldo (voice)