Tom Hanks as Robert Langdon

Ewan McGregor as Camerlengo Patrick McKenna

Ayelet Zurer as Vittoria Vetra

Stellan Skarsgård as Commander Richter

Pierfrancesco Favino as Inspector Olivetti

Nikolaj Lie Kaas as Assassin

Armin Mueller-Stahl as Cardinal Strauss

Thure Lindhardt as Chartrand

David Pasquesi as Claudio Vincenzi

Cosimo Fusco as Father Simeon

Victor Alfieri as Lieutenant Valenti

Franklin Amobi as Cardinal Lamasse

Curt Lowens as Cardinal Ebner

Bob Yerkes as Cardinal Guidera

Marc Fiorini as Cardinal Baggia

Carmen Argenziano as Father Silvano Bentivoglio

Howard Mungo as Cardinal Yoruba

Rance Howard as Cardinal Beck

Steve Franken as Cardinal Colbert

Gino Conforti as Cardinal Pugini

Elya Baskin as Cardinal Petrov

Richard Rosetti as Conclave Cardinal

Silvano Marchetto as Conclave Cardinal

Thomas Morris as Urs Weber

Jonas Fisch as Adrian Bachman

August Wittgenstein as Swiss Guardsman

Ben Bela Böhm as Swiss Guardsman

Paul Schmitz as Swiss Guardsman

Jeffrey Boehm as Swiss Guard Blue

Xavier J. Nathan as Philippe

Steve Kehela as American Reporter

Ursula Brooks as BBC Reporter

Rashmi as British Reporter

Yan Cui as Chinese Reporter

Fritz Michel as French Reporter

Maria Cristina Heller as Italian Reporter

Rafael Petardi as Italian Reporter

Yesenia Adame as Mexican Reporter

Kristof Konrad as Polish Reporter

Masasa Moyo as South African Reporter

Ed Francis Martin as South American Reporter

Cheryl Howard as CERN Scientist

Endre Hules as CERN Scientist

Norbert Weisser as CERN Scientist

Shelby Zemanek as Little Girl in Square

Vanna Salviati as Protester

Raffi Di Blasio as Protester

Todd Schneider as Carabinieri

Roberto Donati as Carabinieri

Rocco Passafaro as Carabinieri

Emanuele Secci as Carabinieri

Anna Katarina as Docent

James Ritz as Tourist

Felipe Torres Urso as Tourist

Jose David Acevedo as Italian Police (uncredited)

Roy Allen III as Cardinal (uncredited)

Tibor Ambra as Carabinieri Captain (uncredited)

Victor of Aquitaine as Vatican Choir Member (uncredited)

Michael Ark as CNN Reporter (uncredited)

John Jason Bailey as Swiss Guard Blue (uncredited)

Jerred Berg as Stem Cell Protestor #2 (uncredited)

Sally Berman as Vatican Square Singer (uncredited)

Yuki Bird as Scientist (uncredited)

Anthony Bonaventura as Vatican Police (uncredited)

Robert Bradvica as Italian Boy (uncredited)

Ciara Bravo as Italian Girl (uncredited)

Michael Patrick Breen as Ukrainian General (uncredited)

Aidan Bristow as Conclave Priest #1 (uncredited)

Cheryl BryantBruce as Diplomat's Wife Vatican Mourner (uncredited)

Raúl Cardona as Piazza Navona Tourist (uncredited)

Christopher Casa as Tourist (uncredited)

Patrick Casa as Choirboy / Tourist (uncredited)

Pasquale Cassalia as Rai Reporter (uncredited)

Farouk Chakwa as Carabinieri (uncredited)

Bacha Chilaia as Carabinieri Sergeant (uncredited)

Jimmy Clabots as Vatican Choir Member (uncredited)

Mark E. Clason as Vatican Choir Member (uncredited)

Tammy Colbert as Vatican Square Gypsy (uncredited)

Austin Michael Coleman as Young Funeral Mourner (uncredited)

Robert Corvin as U.S. Army General (uncredited)

Luca Costa as Fireman (uncredited)

Gina D'Acciaro as Vatican Square Singer (uncredited)

John Dardenne as Swiss Guard Multicolor (uncredited)

William "Will" Daubert as Priest (uncredited)

Shervin Davatgar as Arab Reporter (uncredited)

Blake Dawson as Italian Girl (uncredited)

Vincent De Paul as Vatican Pall Bearer (uncredited)

David Dedinsky as Vatican Cardinal (uncredited)

Lea Deesing as Italian Mourner (uncredited)

Norman Deesing as Italian Mourner (uncredited)

Angelique Deuitch as Tourist (uncredited)

Paul DiVito as Priest (uncredited)

Brant Dorman as Swiss Guard Blue (uncredited)

Allen Dula as Vatican Police Officer (uncredited)

Liz Duran as Vatican Mouner (uncredited)

Matthew Earnest as Italian Mourner (uncredited)

Peter Ettinger as Tourist With Backpack (uncredited)

Jonn Faircrest as Papal Photographer (uncredited)

Les Feltmate as Priest (uncredited)

William Ferguson as Cardinal (uncredited)

Amanda Jane Fleming as Tourist (uncredited)

David Fletcher as Protestor #3 (uncredited)

Gregory George Frank as Protester (uncredited)

Harrison Freed as Tourist (uncredited)

Aaron Denius Garcia as Carabinieri (uncredited)

Nancy Gassner-Clayton as Vatican Square Singer (uncredited)

Justin Giddings as Vatican Choir Member (uncredited)

Phil Gold as Vatican Square Singer (uncredited)

Alan Gray as Greek Patriarch Priest (uncredited)

Marco Greco as Fireman (uncredited)

Roger Groh as Good Bishop (uncredited)

Nancy Guerriero as Vatican Nun (uncredited)

Andrew Hamilton as Swiss Gaurd Multicolored (uncredited)

Martin Harris as Polish Reporter (uncredited)

Miriam Harris as Mourner (uncredited)

Charlie Heydt as Swiss Guard (uncredited)

David Hill as Pantheon Tourist (uncredited)

Kei Hirayama as Scientist (uncredited)

Brett Hunt as Vatican Priest (uncredited)

Marco Infante as Italian Mourner (uncredited)

Clark James as Vatican Policeman (uncredited)

Christopher Karl Johnson as Cardinal (uncredited)

Dave Johnson as Press Photographer (uncredited)

Gina Juliet as Vatican Square Singer (uncredited)

Slim Khezri as Vatican Square Gypsy (uncredited)

Sophiah Koikas as Tourist (uncredited)

Michael Laren as Vatican Choir Singer (uncredited)

Robert W. Laur as Vatican Choir Singer (uncredited)

Adrian Lee as Vatican Square Soloist (uncredited)

David Michael Lewin as Mourner (uncredited)

Maynor Lopez as Carabinieri (uncredited)

Jon Lucero as Vatican Police Officer (uncredited)

Eder López as Italian Citizen (uncredited)

Julie Mabry as Protester in Vatican (uncredited)

Les Mahoney as Hip Priest (uncredited)

Gary Mandarino as Mourner (uncredited)

Albert Marrero Jr. as News Camerman (uncredited)

Stephen Marrero as Priest (uncredited)

Carina Aviles Marshall as Reporter (uncredited)

Debbie McAlister as Reporter (uncredited)

Sandra McCurdy as Italian Tourist (uncredited)

Anthony Molinari as Vatican Guard (uncredited)

Elsa Morales Myers as Tourist (uncredited)

Mary E. Morales as Vatican Square Soloist (uncredited)

Sauvion Morkunas as Flag-bearer (uncredited)

William Myers as Photographer (uncredited)

Manuel Nardi as Priest (Mr. Grey's Men) (uncredited)

Justin Orton as Tourist (uncredited)

Sarita Ospina as Reporter (uncredited)

Dale Pavinski as Carabinieri Captain (uncredited)

Amelia Pawlak as Italian Mourner / Nun (uncredited)

David Pearl as Priest (uncredited)

David Pryor as Mourner (uncredited)

Lawrence Ravettina as Vatican Cardinal (uncredited)

Paul Richard as Swissguard #4 (uncredited)

Jarrod Robbins as Swiss Guardsman (uncredited)

Bertrand Roberson Jr. as Tourist (uncredited)

Adriana Roze as Vatican Square Singer (uncredited)

Franklin Ruehl as Mourner (uncredited)

Kelly Ryan as Protestor #4 (uncredited)

Dylan Saccoccio as Carabinieri (uncredited)

Frank Scozzari as Vatican Police Officer (uncredited)

James Seaman as Costudi (uncredited)

Keith Shawn as Vatican Tourist (uncredited)

Jutta Speidel as Woman (uncredited)

GJ Tiari as The Cryer (uncredited)

Nico Toffoli as Carabieniere Riot (uncredited)

Devin Toft as Carabinieri (uncredited)

James Tumminia as Vatican Priest (uncredited)

Julian Vada as Carabinieri (uncredited)

Ryan Van de Kamp Buchanan as The Swiss Guard (uncredited)

Ernie Ventry as Gypsy in Square (uncredited)

Damon Viola as Mourner (uncredited)

Shannon Watson as Swiss Guard (uncredited)

Denise Winsor as Vatican Nun (uncredited)

Jon Morgan Woodward as The American with the Sign (uncredited)

Allan Yates as Swiss Guard (uncredited)

Alfred Molina as Narrator (voice)