Nicolas Cage as Benjamin Franklin Gates

Diane Kruger as Abigail Chase

Justin Bartha as Riley Poole

Sean Bean as Ian Howe

Jon Voight as Patrick Gates

Harvey Keitel as Peter Sadusky

Christopher Plummer as John Adams Gates

David Dayan Fisher as Shaw

Stewart Finlay-McLennan as Powell

Oleg Taktarov as Shippen

Stephen A. Pope as Phil

Annie Parisse as Agent Dawes

Mark Pellegrino as Agent Johnson

Armando Riesco as Agent Hendricks

Erik King as Agent Colfax

Don McManus as Stan Herbert

Ron Canada as Guard Woodruff

Hunter Gomez as Young Ben Gates

Deborah Yates as Rebecca

Arabella Field as Abigail's Secretary

Sharon Wilkins as Butcher Lady

Alexandra Balahoutis as Clothing Store Clerk

Dior Raye as Gift Store Clerk

Yves Beneche as Museum Kid

Jason Earles as Thomas Gates

Terrence Currier as Charles Carroll

Rod McLachlan as Independence Hall Guide

Elizabeth Greenberg as Liberty Bell Guide

Jody Halse as Franklin Institute Guard

Liam Noble as Franklin Institute Security

Joshua Bitton as Technician

Michael Russo as Popcorn Vendor

Fern D. Baguidy Jr. as Gala Guard

Thomas Q. Morris as Janitor

Antony Alda as Guard Ferguson

John Travis as Guard Mike

Adriana Alveario as Shopper at Market (uncredited)

Frank Anello as FBI Agent (uncredited)