John Wayne as Capt. Nathan Cutting Brittles

Joanne Dru as Olivia Dandridge

John Agar as Lt. Flint Cohill

Ben Johnson as Sgt. Tyree

Harry Carey, Jr. as 2nd Lt. Ross Pennell

Victor McLaglen as First Sergeant Quincannon

Mildred Natwick as Abby Allshard ("Old Iron Pants")

George O'Brien as Maj. Mac Allshard

Arthur Shields as Dr. O'Laughlin

Michael Dugan as Sgt. Hochbauer

Chief John Big Tree as Chief Pony That Walks

Fred Graham as Sgt. Hench

George Sky Eagle as Chief Sky Eagle

Tom Tyler as Cpl. Mike Quayne

Noble Johnson as Chief Red Shirt

Paul Fix as Gunrunner (uncredited)

Francis Ford as Connelly - Fort Stark Suttlers Barman (uncredited)

Cliff Lyons as Trooper Cliff (uncredited)

Frank McGrath as Bugler / Indian (uncredited)

Irving Pichel as Narrator (voice) (uncredited)

William Steele as Officer (uncredited)

Jack Tornek as Officer (uncredited)

Dan White as Trooper (uncredited)

Harry Woods as Karl Rynders (uncredited)

Peter Ortiz as Gunrunner (uncredited)

Rudy Bowman as Pvt. John Smith - aka Rome Clay (uncredited)

Lee Bradley as Interpreter (uncredited)

Ray Hyke as Trooper McCarthy (uncredited)

Billy Jones as Courier (uncredited)

Fred Kennedy as Badger (uncredited)

Fred Libby as Cpl. Krumrein (uncredited)

Evelyn Moriarty as Party Guest (uncredited)

Post Park as Officer (uncredited)

Jack Pennick as Sergeant Major (uncredited)

Mickey Simpson as Cpl. Wagner (uncredited)

Don Summers as Jenkins (uncredited)