William Powell as Nick Charles

Myrna Loy as Nora Charles

Lucile Watson as Mrs. Marta Charles

Gloria DeHaven as Laura Belle Ronson

Anne Revere as Crazy Mary

Helen Vinson as Helena Draque

Harry Davenport as Dr. Bertram Charles

Leon Ames as Edgar Draque

Donald Meek as Willie Crump

Edward Brophy as Brogan

Lloyd Corrigan as Dr. Bruce Clayworth

Anita Sharp-Bolster as Hilda

Ralph Brooke as Peter Berton

Donald MacBride as Police Chief MacGregor

Morris Ankrum as Willoughby Peavy

Nora Cecil as Miss Peavy

Minor Watson as Sam Ronson

Irving Bacon as Tom

Virginia Sale as Tom's Wife

Asta Jr. as Asta