William Powell as Nick Charles

Myrna Loy as Nora Charles

Barry Nelson as Paul Clarke

Donna Reed as Molly Ford

Sam Levene as Lieutenant Abrams

Alan Baxter as 'Whitey' Barrow

Henry O'Neill as Major Jason I. Sculley

Richard Hall as Nick Charles, Jr.

Stella Adler as Claire Porter

Loring Smith as 'Link' Stephens

Joseph Anthony as Fred Macy

Lou Lubin as 'Rainbow' Benny Loomis

Louise Beavers as Stella

Skippy as Asta

Oliver Blake as Lawyer Fenster

Adeline DeWalt Reynolds as Barrows' Landlady (uncredited)

George Lloyd as Pipey (uncredited)

Sid Melton as Fingers (uncredited)

Jody Gilbert as Lana Webb (uncredited)

Tor Johnson as "The Irish Thrush", a wrestler (uncredited)

The Cardiff Giant as Bearded Wrestler (uncredited)

Ava Gardner as Passerby at Racetrack (uncredited)

John George as Wrestling Match Spectator (uncredited)

Aldrich Bowker as Watchman (uncredited)

H.B. Haggerty as Mug

Al Bain as Wrestling Match Spectator (uncredited)

Arthur Aylesworth as Second Coroner (uncredited)

Tom Coleman as Cop (uncredited)

Joe Devlin as Mug Starting Fight at Wrestling Match (uncredited)

Fred Graham as Waiter with Steak (uncredited)

Herschel Graham as Wrestling Match Spectator (uncredited)

Joey Ray as Stephens' Clerk (uncredited)

Ray Teal as Cab Driver (uncredited)

Will Wright as Maguire - Nervous Ticket Seller (uncredited)