Jamie Foxx as Alvin Sanders

David Morse as Edgar Clenteen

Robert Pastorelli as Jaster

Doug Hutchison as Bristol

Kimberly Elise as Lisa Hill

David Paymer as Agent Wooly

Mike Epps as Stevie Sanders

Jamie Kennedy as Agent Blum

Nestor Serrano as Agent Boyle

Kirk Acevedo as Ramundo

Jeffrey Donovan as Julio

Megan Dodds as Agent Walsh

Tia Texada as Tika

Neil Crone as Supervisor

Jason Jones as Guard

Martin Roach as Cop

Matthew Witherly as Guard

William Lynn as Night Watchman

Glyn Thomas as Chem-Tech Agent

Victor A. Young as Senator

Don Allison as Senator

Paul Miller as Dr. Harris

Goûchy Boy as Convict

Arnold Pinnock as Convict

Clé Bennett as Convict

Desmond Campbell as Convict

Shawn Lawrence as Warden Clay

Lee Rumohr as Bound Guard

Norm Spencer as Bound Guard

Tom Cappadona as Cab Driver

Jonathan Hadary as Cafe Owner

Ritchie Coster as Buyer

Stan Coles as General

Larry Block as Customer

Billy Otis as Odd Inmate

Navaco Bernice Downey as Girl in Club

John 'Frenchie' Berger as Medical Examiner

Joe Pingue as Cop

John Harper as Running Man

Dylan Bierk as Police Photographer

Bruce Beaton as Agent with Coffee

Ron Kennell as Mobile Agent

Conrad Bergschneider as Mobile Agent

Nik Pjeternikaj as Agent

Ron Bell as Trucker

Joanna Polley as Rhonda Glimsher (voice)

Lorraine McNeill-Krall as Woman Looking in Car Window

Brian Donahue as Federal Officer (uncredited)

David Headon as NSA Guard (uncredited)

Donna Milburn as Dancer (uncredited)

Jennifer Newman as Featured Dancer (uncredited)

Nick Poltoranin as FBI Agent (uncredited)

Paul Calderon as Cop (uncredited)

Wesley Finucan as Crowd Member (uncredited)

Antoine Fuqua as Man (uncredited)

Steve Nuke as FBI Agent (uncredited)

Matthew Reid as Man Running to the Bathroom (uncredited)