Dakota Fanning as Coraline Jones (voice)

Teri Hatcher as Mel Jones / Other Mother (voice)

Jennifer Saunders as Miss April Spink / Other Spink (voice)

Dawn French as Miss Miriam Forcible / Other Forcible (voice)

Keith David as The Cat (voice)

John Hodgman as Charlie Jones / Other Father (voice)

Robert Bailey Jr. as Wyborne 'Wybie' Lovat (voice)

Ian McShane as Mr. Sergei Alexander Bobinsky / Other Bobinsky (voice)

Aankha Neal as Sweet Ghost Girl (voice)

George Selick as Ghost Boy (voice)

Hannah Kaiser as Tall Ghost Girl (voice)

Harry Selick as Photo Friend (voice)

Marina Budovsky as Photo Friend (voice)

Emerson Tenney as Magic Dragonfly (voice)

Jerome Ranft as Mover (voice)

Christopher Murrie as Toy (voice)

Jeremy Ryder as Toy (voice)

Carolyn Crawford as Wybie's Grandmother (voice)

Yona Prost as Shakespeare Rascal (voice)

John Linnell as Other Father (singing voice) (uncredited)