Michael Cera as Fred

Jamie Kennedy as Mateus

Matthew Lillard as Self

Frankie Muniz as Chuck

Ryan Pinkston as Mike

Patrick J. Adams as Male Voice (voice)

Denise Boutte as New Tabitha

Brian Burt as Dancer

Rich Ceraulo Ko as Angus

Vanessa Lee Chester as Charlotte

Dennis Cockrum as Len's Dad

Byron Cotton as David

Nicholas D'Agosto as Evan

Shasa Dabner as Lindsey

Christina DeRosa as Nancy

James Eckhouse as Jessica's Dad

Danny Ehrhardt as Biff

Jane Silvia as Female College Student

John Farley as Mr. Matthews

Meagen Fay as Len's Mom

Ben Feldman as Len

Dan Finnerty as Gigundocock

Adam Frost as Male College Student

Simona Fusco as Hot Blonde

JoAnna Garcia Swisher as Sweetie-Pie

Kyle Gass as Director

Murray Gershenz as Jake

Brentley Gore as Assistant Director

Dona Hardy as Molly

Danneel Ackles as Melissa

Hank Harris as Ronny

Margo Harshman as Ted's Girlfriend

Kevin Hart as Barry

Heather Hogan as Kat

Kyle Howard as Boyfriend

Antonio Hudnell as Dancer

Donna Kimball as Blue Bally (voice)

Kendra Krull as Judy

Vanessa Lengies as Carla

Philip Lenkowsky as Clerk

Margie Loomis as Older Lady

Bobbi Sue Luther as Gabriela

Sonia Rockwell as Kim

Cristin Michele as Jackie

Andy Milonakis as Justin

Beverley Mitchell as Sue

'Big' LeRoy Mobley as Guy #2

Ms. P. as Tabitha

Steven Christopher Parker as Doug

Marcus T. Paulk as Wyatt

Rob Pinkston as Griffin

Allison Queal as Little Person #2

Shacolby Randell as Guy #1

Luigi Francis Shorty Rossi as Little Person #1

Jake Sandvig as Hank

Ashley Schneider as Betty

Rachel Specter as Blonde

Mindy Sterling as Jane

Jeremy Suarez as RJ

Anne Son as Roommate

Ed Trotta as Lincoln

Kira Verrastro as Chick

Katie Walder as Drunk Girl

Rheagan Wallace as Jessica

Jermaine Williams as Leon

Cherilyn Wilson as Stacy

Mika Winkler as Little Person #3

Royal Binion as Basketball Boner Guy (uncredited)

Pat Brymer as Blue Bally (uncredited)

Chris Cooper as FBI Agent Mike (uncredited)

Blake French as Basketball Guy (uncredited)

Aaron Haedt as Guy in Underwear (uncredited)

Lisa Richman as Jessica's Mom (uncredited)

John Westernoff as Guy in Underwear (uncredited)