Howard Stern as Howard Stern

Robin Quivers as Robin Quivers

Mary McCormack as Alison Stern

Fred Norris as Fred Norris

Paul Giamatti as Kenny

Gary Dell'Abate as Gary Dell'Abate

Jackie Martling as Jackie Martling

Carol Alt as Gloria

Richard Portnow as Ben Stern

Kelly Bishop as Ray Stern

Henry Goodman as Moti

Jonathan Hadary as Griff

Paul Hecht as Ross Buckingham

Allison Janney as Dee Dee

Michael Murphy as Roger Erlick

James Murtaugh as Payton

Reni Santoni as Vallesecca

Lee Wilkof as Marvin Mamoulian

Melanie Good as Brittany Fairchild

Theresa Lynn as Orgasm Woman

Amber Smith as Julie

Althea Cassidy as The Kielbasa Queen

Jenna Jameson as Mandy

Bobby Boriello as Seven-Year-Old Howard

Michael Maccarone as 12-year-old Howard

Matt Friedman as 16-year-old Howard

John Michael Bolger as Music Awards Technician

John Stamos as John Stamos

Christopher Barron as Chris Barron

Flavor Flav as Flavor Flav

MC Hammer as M.C. Hammer

Ted Nugent as Ted Nugent

Ozzy Osbourne as Ozzy Osbourne

Slash as Slash

Renee Suran as Renee Suran

Dee Snider as Dee Snider

Tiny Tim as Tiny Tim

John Popper as John Popper

Steven Gilborn as Howard's Agent

Curtis McClarin as Airline Representative

Richard B. Shull as Symphony Sid

Evan Roberts as Elliot

Gabriel De Silva as Herbie

Jennifer Gareis as Coed

Mandy Fabian as Coed

Ali Marsh as Blind Coed

Scott Cohen as Friend

James Villemaire as Friend

Wendy Hoopes as Elyse

Richard Russell Ramos as Film Professor

Gordon Joseph Weiss as Unshaven Deejay

Allison Furman as Barb

Julie Gawkowski as Patricia Fonfara

Davenia McFadden as Nurse

Michael C. Gwynne as The Duke of Rock

Irene DeCook as Leather Weather Lady

Jordan Derwin as Rubberbound Man

Silas Weir Mitchell as Patient

Stuart Rudin as Trembling Patient

Richard Ziman as Salesman

Adam LeFevre as Sales Manager

Janine Lindemulder as Camp Director's Wife

Scott Lawrence as News Guy

Christine Tucci as Doctor

Kim Chan as Waiter

Nicholas Wyman as Douglas Kiker

Stephen Pearlman as Couple Looking for Apartment

Catherine Wolf as Couple Looking for Apartment

Tom Tammi as Corporate Executive

Luke Reilly as Imus

Rick Levi as Lawyer

Peter Jacobson as Lawyer

Leslie Bibb as NBC Tour Guide

Joanne Camp as Reenie

Peter Maloney as Researcher

Sarah Zinsser as Kenny's Secretary

Barry Papick as Engineer

David Letterman as David Letterman

Christine Toy Johnson as NBC Switchboard Operator

Alison Stern as NBC Switchboard Operator

Brian Johnson as Brian Johnson - AC/DC Singer

Angus Young as Angus Young - AC/DC Lead Guitar

Malcolm Young as Malcolm Young - AC-DC Rhythm Guitar

Phil Rudd as Phil Rudd - AC-DC Drummer

Cliff Williams as Cliff Williams - AC-DC Bassist

Susan Pratt as Stewardess

Sasha Martin as Howard's Daughter

Sarah Hyland as Howard's Daughter

John Melendez as John Melendez

Crackhead Bob as Crackhead Bob

Nicole Bass-Fuchs as Nicole Bass

Camille Meyer as Bikini Girl in Westchester

Danna Bradley as Transvestite

Seth Silver as Transvestite

Carrie Flaska as Wife in Car

Steve Ballot as Husband

Brian Costantini as DC Cop

Barnett Milton Lloyd as DC Cop

Aimee Luzier as Betty Jean Rushton (voice)

Mary Lou Allgood as Lesbian Harem Girl (uncredited)

Alley Baggett as Girl in Lesbian Camp (uncredited)

Lawrence Cioppa as Alison's Father (uncredited)

Garrett Cassell as Clown (uncredited)

Wilson Cleveland as Concertgoer (uncredited)

Joe Tom Collins as College Student (uncredited)

Peter Costanza as Extra (uncredited)

Mary Dimino as Autograph Seeker (uncredited)

Patrick Coleman Duncan as Film School Student (uncredited)

Edie Falco as Alison's Friend (uncredited)

Mia Farrow as Mia Farrow (uncredited)

Tommy Grillo as Audience Member (uncredited)

Larry Guardino as Passerby (uncredited)

Barry Hirschberg as Background Extra (uncredited)

Sonia Kazarova as Escort to John Stamos - MTV Music Awards (uncredited)

James Koons as Rally Goer (uncredited)

Marshall Dancing Elk Lucas as Guy (uncredited)

James Murray as Student (uncredited)

Joy Newman as Mary Magdalene - Howard's College Film Project (uncredited)

Iggy Pop as Iggy Pop (uncredited)

Rico Racine as NBC Studio Guy (uncredited)

Kevin Scullin as Disc Jockey at WCCC (uncredited)

Kennen Sisco as Autograph Girl (uncredited)

David Sontag as Biker (uncredited)

Matilda Szydagis as Audience Member (uncredited)

Larry Tobias as Man in Crowd (uncredited)

Emmanuel Todorov as Audience Member (uncredited)

Christopher Tracy as Concert Guard (uncredited)

J.D. Walters as Autograph Seeker (uncredited)

Christopher White as Student (uncredited)

Wendy Whoppers as Big-Breasted Woman (uncredited)

Stewart J. Zully as Dicky Davis (uncredited)