Diane Keaton as Marilyn Cooper

Dax Shepard as Noah Cooper

Liv Tyler as Clare Cooper

Ken Howard as Gene Cooper

Jerry Lambert as Donnie Booker

Selma Stern as Helen Cooper

Mike White as Myron Stubbs

Steven Christopher Parker as Dana

Henriette Ivanans as Therapy Receptionist

Frank Crim as Bob

Eddie Frierson as Ralph

James Taku Leung as Hartanto

Matt Steinauer as Carpet Bazaar Mascot

Rachel Cannon as Waitress

Tara Moore as Pippi

Lucas Gorak as Tommy

Alexandra Murdy as Annika

Carlos McCullers II as Basset Hound

Taj Hester as Beagle

Cindy Clark as Barbara

Jacque Lynn Colton as Cindy

Celeste Damron as Pain Pal

Sharon Di Meglio as Pain Pal

Dawn Rasmussen as Pain Pal

Judy Nishimine as Pain Pal

Ron Butler as Friendly Man

Johnny Hagen as Karaoke Singer

Jess Rowland as Karaoke DJ

Jerry Sherman as Art

Cletus Young as Sam

Don Lake as Minister

Sarah Lancaster as Holly

Cameron Bender as Jim

Skip Stellrecht as MAX 9000 (voice)

Steven Fernandez as Clare's Second Grade Student

Lilly Henderson as Clare's Second Grade Student

Laila Kazerooni as Clare's Second Grade Student

Luis Lefort as Clare's Second Grade Student

Adrien Ochoa as Clare's Second Grade Student

Curtis Olson as Clare's Second Grade Student

Ashley Person as Clare's Second Grade Student

Franklin Ramirez as Clare's Second Grade Student

Amar Ross as Clare's Second Grade Student

Julianna Saigusa as Clare's Second Grade Student

Kimberly Bosso as Baby Shower Guest (uncredited)

George Kendall as Tony (uncredited)

Ket Lamb as Vacuum Cleaning Gag Lady (uncredited)

Julio Macat as Carpet Bazaar Customer (uncredited)

Sonia Perozzi as Waitress (uncredited)