Charlie Adler as Low-Light (voice)

Shuko Akune as Jinx (voice)

Jack Angel as Wet-Suit (voice)

Michael Bell as Duke / Xamot / Blowtorch / Lift Ticket (voice)

Gregg Berger as Motorviper (voice)

Earl Boen as Taurus (voice)

Arthur Burghardt as Destro / Iceberg (voice)

Corey Burton as Tomax (voice)

William Callaway as Beach Head (voice)

François Chau as Quick Kick (voice)

Peter Cullen as Zandar / Nemesis Enforcer / Scientist (voice)

Brian Cummings as Dr. Mindbender (voice)

Jennifer Darling as Pythona (voice)

Richard Gautier as Serpentor (voice)

Ed Gilbert as General Hawk (voice)

Dan Gilvezan as Slip Stream (voice)

Laurie Faso as Tunnel Rat (voice)

Don Johnson as Lt. Falcon (voice)

Zack Hoffman as Zartan (voice)

Kene Holliday as Roadblock (voice)

John Hostetter as Bazooka (voice)

Vernee Watson-Johnson as Scientist (voice)

Buster Jones as Doc (voice)

Mary McDonald-Lewis as Lady Jaye (voice)

Morgan Lofting as Baroness (voice)

Chuck McCann as Leatherneck (voice)

Michael McConnohie as Cross-Country (voice)

Burgess Meredith as Golobulus (voice)

Ron Ortiz as Law (voice)

Rob Paulsen as Snow Job (voice)

Patrick Pinney as Mainframe (voice)

Poncie Ponce as Red Dog (voice)

Lisa Raggio as Heather / Zarana (voice)

Bill Ratner as Flint (voice)

Neil Ross as Buzzer / Shipwreck / Hector Ramirez / Monkeywrench (voice)

Brad Sanders as Big Lob (voice)

Ted Schwartz as Thrasher (voice)

Robert Remus as Sgt. Slaughter (voice)

Kristoffer Tabori as Mercer (voice)

B.J. Ward as Scarlett (voice)

Lee Weaver as Alpine (voice)

Frank Welker as Torch / Wild Bill (voice)

Stan Wojno as Lifeline (voice)

Jackson Beck as Narrator (voice)

Christopher Collins as Cobra Commander / Gung Ho / Ripper / Televiper #1 (voice)