Josh Lucas as Col. Roy Manley

Mira Sorvino as Sally Hawkins

Dermot Mulroney as Andy Hawkins

Booboo Stewart as Conway

Danny Glover as Commander Phillips

Thomas Horn as Jimmy Hawkins

Grayson Russell as Russell 'Rusty' Riggs

Ryan Simpkins as Lacey

Savannah Jayde as Dani Williams

Michael Zhang as Bao Yuen

Sahana Srinivasan as Chandra

Nicholas Lobue as Sergei Petrov

Thomas Kasp as Hunter

Chris Ashworth as Cosmonaut Yuri

Rico Ball as Astronaut Michael

Dawn Ferry as Astronaut Molly

Tucker Moore as Tech #1

Ken Feinberg as Tech #2

Natasha Pavlovich as Russian Tech #1

Randall Taylor as Russian Tech #2

Deborah Barnhart as Dr. Deborah Barnhart

Mike Flachbart as Mission Controller

Danny Vinson as NASA Exec #1

Robert W. Hill as NASA Exec #2

Sharon Gee as Bao's mom

David Wesley Scott as Mr. Petrov

Drake Bell as Jimmy Narration (voice)

Robert Tur as Newscaster #1

Mike Theiss as Newscaster #2

Megan Alexander as Newscaster #3

Alana Grace as Newscaster #4

Janet Ivey as Newscaster #5

Tim Hall as Newscaster #6

Morgan Proffer as Sam

Katie Seeley as Alana

Sean McNamara as Marshall Flight Director

Jeremy Sande as Soyuz Commander

Keith Edwards as Rusty's father

Chris Michael Klebba as Robonaut

Charlie Duke as Charlie Duke

Alex Rennekamp as Tops

Sara Biwer as Tops

Amber Flanagan as Family Member

Alan McCrispin as Extra

Debbie Mitchell as Extra

Daniel Christopher Paige as Jimmy

Kim Rost as Dani's Mom

Harrison Stone as Moon Buggy Driver

Sampley Barinaga as Space Cadet (uncredited)

Melissa Bender as Camp Counselor (uncredited)

Grayson Thorne Kilpatrick as Boy in Green at Ceremony (uncredited)