Tom Cruise as David Aames

Penélope Cruz as Sofia Serrano

Cameron Diaz as Julie Gianni

Kurt Russell as Curtis McCabe

Jason Lee as Brian Shelby

Noah Taylor as Edmund Ventura

Timothy Spall as Thomas Tipp

Tilda Swinton as Rebecca Dearborn

Michael Shannon as Aaron

Delaina Mitchell as David's Assistant

Shalom Harlow as Colleen

Oona Hart as Lynette

Ivana Miličević as Emma

Johnny Galecki as Peter Brown

Jhaemi Willens as Jamie Berliner

Armand Schultz as Dr. Pomeranz

Cameron Watson as Other Doctor

Robertson Dean as Third Doctor

W. Earl Brown as Barman

Ray Proscia as Doctor from Berlin

Tim Hopper as Man in Blue Coat

Alicia Witt as Libby

Ken Leung as Art Editor

Carolyn Byrne as Beatrice

Mark Pinter as Carlton Kaller

Jeff Weiss as Raymond Tooley

Conan O'Brien as Conan O'Brien

James Murtaugh as Benny's Owner

Mark Kozelek as Dude, Fix Your Face Guy

John Fedevich as Silent Ed Vallencourt

Bobby Walsh as Young David

Stacey Sher as Rayna

Fred Schruers as Cryo Man

Jessica Siemens as Sofia's Friend

Julia Carothers Hughes as Sofia's Friend

Holly Raye as Dancer

Marty Collins as Martini Waiter

Mark Bramhall as Sneezy

Jack Hall as Bashful

David Lewison as Sleepy

Jennifer Griffin as Happy

Adam LeGrant as Doc

John Kepley as Dopey

Robin Van Sharner as Grumpy

Laurel Wiley as Dr. Jennifer Ash

Nicole Taylor Hart as Party Videographer

Julia Decker as Model

Jennifer Marie Kelley as Model

Erin McElmurry as Model

Alice Marie Crowe as Lucid Dreamer

Mel Thompson as Life Extension Man

Jonathan Sanger as Frozen Pediatric Cardiologist

Tommy Lee as Frozen Vintage Car Man

Ana Maria Quintana as Frozen Theologist

Paul Haggar as Frozen Risktaker

Randy Woodside as Frozen Dad

Robert F. Harrison as Laughing Guy

Carly Starr Brullo Niles as Carly

Jane Pratt as Jane Pratt

Patrick McMullen as Patrick McMullen

Steven Colvin as Steven Colvin

Cindy Crowe as Cindy Crowe

John Sypolt as John Sypolt

Michael G. Kehoe as Chef

Danielle Wolff as Coat Check Girl

Scotch Ellis Loring as L.E. Building Guard

Brent Sexton as Security Guard

Curt Skaggs as Security Guard

Jennifer Gimenez as Lola

Lori Lezama as Skyscraper Girl

Todd Harrison as Skyscraper Guy

Laura Fraser as The Future

Steven Spielberg as Self (uncredited)

Jennifer Aspen as Nina (uncredited)

Celina Belizan as Luli (uncredited)

Craig Callow as Clubgoer (uncredited)

Jean Carol as Woman Nearby (uncredited)

Tony Collucci as Guy at Party (uncredited)

Janine Foster as Dancer (uncredited)

Zach Hudson as Life Extension Security Guard (uncredited)

Ryan Keating as SWAT Team Officer (uncredited)

Roger Lim as SWAT Team Officer (uncredited)

Tara Lipinski as Girl at Party (uncredited)

William Mapother as Clubgoer (uncredited)

Christy Meyers as Girl in Office (uncredited)

Jan Munroe as Older Editor (uncredited)

Marie Paquim as Extra (uncredited)

Ronald Rand as Investigator (uncredited)

Tasha Tae as Dancer (uncredited)

Bryan Todd as Dancer (uncredited)

Christie Will Wolf as Waiting Room Model (uncredited)