Tom Cruise as Ethan Hunt

Dougray Scott as Sean Ambrose

Thandiwe Newton as Nyah Hall

Ving Rhames as Luther Stickell

Richard Roxburgh as Hugh Stamp

John Polson as Billy Baird

Brendan Gleeson as McCloy

Rade Šerbedžija as Dr. Nekhorvich

William Mapother as Wallis

Dominic Purcell as Ulrich

Mathew Wilkinson as Michael

Nicholas Bell as McCloy's Accountant

Cristina Brogeras as Flamenco Dancer #4

Kee Chan as McCloy's Chemist

Kim Fleming as Larrabee

Alan Lovell as Biocyte Security Guard #2

Dan Luxton as Relief Pilot

Christian Manon as Dr. Gradsky

Karl McMillan as Biocyte Security Guard #1

Lester Morris as Bookie

Kelly Ons as Flamenco Dancer #1

Nicholas Papademetriou as Prison Guard #2

Brett Partridge as Biocyte Security Guard #3

Candice Partridge as Flamenco Dancer #7

Natalie Reis as Flamenco Dancer #2

Daniel Roberts as Co-Pilot

Adriana Rodríguez as Flamenco Dancer #5

Sandra Rodríguez as Flamenco Dancer #6

Nada Rogic as Flamenco Dancer #3

Antonio Vargas as Senor De L'Arena

Anthony Hopkins as Mission Commander Swanbeck (uncredited)

Alison Araya as Girl (uncredited)

Rebecca Barratt as Art Teacher (uncredited)

Douglas Bunn as Race Track Crowd (uncredited)

Caine as Race Track Punter (uncredited)

Fred Chen as Club Patron (uncredited)

Mark Connolly as Gate Guard #1 (uncredited)

Ryder Davis as Server (uncredited)

Alan Hennessy as Race-goer (uncredited)

Patrick Marber as Train Driver (uncredited)

William Morts as Man with Mission Rocket in Helicopter (uncredited)

Tory Mussett as Flamenco Guest (uncredited)

Paul Roget as Spanish Party Goer (uncredited)

Shant Sarkissian as Party Attendant (uncredited)

Darren Dupree Washington as Nightclub Patron (uncredited)